Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 1.00 |
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | AGTR1 | P30556 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | MITF | O75030 | 1/20 | 1.00 |
| ▸ | S1PR4 | O95977 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | S1PR1 | P21453 | 1/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | CKS1B | P61024 | 1/20 | 1.00 |
| ▸ | SKP2 | Q13309 | 1/20 | 1.00 |
| ▸ | GLO1 | Q04760 | 7/20 | 0.76 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.76 |
| ▸ | G6PD | P11413 | 1/20 | 0.76 |
| ▸ | METAP2 | P50579 | 1/20 | 0.76 |
| ▸ | METAP1 | P53582 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337402 | 0.99 | TDP1 (0.97) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL5572103 | 0.99 | TDP1 (0.97) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL15299831 | 0.99 | TDP1 (0.97) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL17067733 | 0.89 | TDP1 (0.81) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL13485950 | 0.89 | SLC40A1 (0.80) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL27214217 | 0.87 | SLC40A1 (0.82) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL30925445 | 0.87 | SLC40A1 (0.82) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL442367 | 0.87 | SLC40A1 (1.00) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL6688368 | 0.86 | SLC40A1 (0.85) | TDP1SLC40A1KMT2AAGTR1LMNA | |
| SCHEMBL30553440 | 0.86 | SLC40A1 (0.85) | TDP1SLC40A1KMT2AAGTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436371-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | Call, Krimhild (DE) | 2004-07-14 | — | — | EP | claimed |
| WO-2002099023-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | CALL, KRIMHILD (DE) | 2002-12-12 | — | — | WO | claimed |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-06-04 | — | — | US | disclosed |
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ZOETIS LLC | 2024-05-09 | — | — | US | disclosed |
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | OTAGO INNOVATION LIMITED (NZ) | 2023-07-04 | — | — | US | disclosed |
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | OTAGO INNOVATION LIMITED (NZ) | 2023-07-04 | — | — | US | disclosed |
| CN-111566116-B | Novel metal complex, process for producing the same, and process for producing gamma-lactam compound using the same | 基础科学研究院 | 2023-06-09 | — | — | CN | disclosed |
| US-11413278-B2 | Compounds and methods for promoting stress resistance | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-16 | — | — | US | disclosed |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-06-02 | — | — | US | disclosed |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-05-31 | — | — | US | disclosed |
| US-11213701-B2 | Neuroprotective quinoline sulfonamides | DAHL RUSSELL (US) | 2022-01-04 | — | — | US | disclosed |
| US-7585859-B2 | PDE4B inhibitors and uses therefor | PLEXXIKON, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-20060041006-A1 | PDE4B inhibitors and uses therefor | PLEXXIKON, INC. | 2006-02-23 | — | — | US | disclosed |
| EP-1436371-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | Call, Krimhild (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0675358-B1 | Monitoring water treatment agent in-system concentration and regulating dosage | NALCO CHEMICAL CO (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002099023-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | CALL, KRIMHILD (DE) | 2002-12-12 | — | — | WO | disclosed |
| EP-0675358-A1 | Monitoring water treatment agent in-system concentration and regulating dosage | NALCO CHEMICAL COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |
| US-4209419-A | Certain sulfonamidoquinolines, metal complexes thereof, and solutions containing such sulfonamidoquinolines and metal complexes | HENKEL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4100163-A | Substituted 8-sulfonamidoquinolines | GENERAL MILLS CHEMICALS, INC. (US) | 1978-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | TDP1 4645/4885SLC40A1 2128/4885KMT2A 1875/4885 |
| US-11213701-B2 | Neuroprotective quinoline sulfonamides | SUMO3, SUMO2, PSEN1 | TDP1 522/4885SLC40A1 4609/4885KMT2A 2060/4885 |
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | NQO2, SDHA, SIRT5 | TDP1 4605/4885SLC40A1 4081/4885KMT2A 1680/4885 |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | TDP1 4620/4885SLC40A1 2215/4885KMT2A 1518/4885 |
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ARSA, MRPS2, SULT2A1 | TDP1 4247/4885SLC40A1 3357/4885KMT2A 1323/4885 |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | TDP1 4620/4885SLC40A1 2215/4885KMT2A 1518/4885 |
| US-20060041006-A1 | PDE4B inhibitors and uses therefor | PDE4B, PDE7B, PDE4A | TDP1 83/4885SLC40A1 4638/4885KMT2A 2234/4885 |
| US-11413278-B2 | Compounds and methods for promoting stress resistance | HSPA9, ATF4, GPX4 | TDP1 2088/4885SLC40A1 1579/4885KMT2A 2884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.