Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733277 | 0.89 | S100B (0.82) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL10412841 | 0.89 | S100B (0.82) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL2010515 | 0.89 | S100B (0.82) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL12416630 | 0.89 | S100B (0.82) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL10733285 | 0.89 | S100B (0.82) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL12416663 | 0.84 | S100B (0.74) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL16488576 | 0.82 | S100B (0.72) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL13038178 | 0.82 | S100B (0.72) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL11380636 | 0.82 | S100B (0.72) | S100BPTGS2CA2PTGS1CA12 | |
| SCHEMBL269057 | 0.82 | S100B (0.72) | S100BPTGS2CA2PTGS1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-09-28 | — | — | US | disclosed |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | TST, SDHB, NDUFS3 | S100B 280/4885PTGS2 664/4885CA2 4103/4885 |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | TST, SDHB, NDUFS3 | S100B 280/4885PTGS2 664/4885CA2 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.