Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775556 | 0.79 | P2RX7 (0.47) | ALDH1A1HPGDCYP2C19CYP1A2MEN1 | |
| SCHEMBL29431236 | 0.79 | P2RX7 (0.47) | ALDH1A1HPGDCYP2C19CYP1A2MEN1 | |
| SCHEMBL22775433 | 0.78 | KMT2A (0.48) | ALDH1A1HPGDCYP2C19KDM4ECYP3A4 | |
| SCHEMBL29431173 | 0.78 | KMT2A (0.48) | ALDH1A1HPGDCYP2C19KDM4ECYP3A4 | |
| SCHEMBL22787649 | 0.75 | MEN1 (0.40) | ALDH1A1HPGDCYP2C19KDM4ECYP3A4 | |
| SCHEMBL3583563 | 0.67 | PTGER1 (0.47) | ALDH1A1CYP2C19KDM4ECYP3A4CYP1A2 | |
| SCHEMBL4803702 | 0.66 | NPBWR1 (0.50) | ALDH1A1HPGDCYP2C19KDM4ECYP3A4 | |
| SCHEMBL29158354 | 0.66 | TLR7 (0.46) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL1491059 | 0.64 | NPBWR1 (0.48) | ALDH1A1CYP2C19KDM4ECYP3A4CYP1A2 | |
| SCHEMBL24798906 | 0.61 | FPR1 (0.48) | ALDH1A1HPGDCYP2C19KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249957-A1 | COMPOUNDS FOR TREATING RESPIRATORY DISEASE | Enterprise Therapeutics Limited (GB) | 2020-12-17 | — | — | WO | disclosed |