Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431173 | 1.00 | KMT2A (0.48) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL29659774 | 0.79 | KMT2A (0.43) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL22787644 | 0.78 | ALDH1A1 (0.46) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL29613695 | 0.77 | MEN1 (0.41) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL28656371 | 0.71 | HTT (0.37) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL3208212 | 0.70 | MAPT (0.60) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL3217202 | 0.69 | MAPT (0.46) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL22775556 | 0.69 | P2RX7 (0.47) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1666611 | 0.67 | KEAP1 (0.48) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL1666034 | 0.67 | SLC29A1 (0.46) | KMT2AMAPTMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552770-B2 | Compounds for treating respiratory disease | TMEM16A LIMITED (GB) | 2026-02-17 | — | — | US | disclosed |
| EP-3983389-A1 | COMPOUNDS FOR TREATING RESPIRATORY DISEASE | TMEM16A LIMITED (GB) | 2022-04-20 | — | — | EP | disclosed |
| US-20220098167-A1 | COMPOUNDS FOR TREATING RESPIRATORY DISEASE | TMEM16A LTD (GB) | 2022-03-31 | — | — | US | disclosed |
| WO-2020249957-A1 | COMPOUNDS FOR TREATING RESPIRATORY DISEASE | Enterprise Therapeutics Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020249957-A1 | COMPOUNDS FOR TREATING RESPIRATORY DISEASE | Enterprise Therapeutics Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552770-B2 | Compounds for treating respiratory disease | TMEM109, SCN1A, SLC16A1 | KMT2A 1602/4885MAPT 1158/4885MEN1 1176/4885 |
| US-20220098167-A1 | COMPOUNDS FOR TREATING RESPIRATORY DISEASE | TMEM109, SLC16A1, CFTR | KMT2A 3542/4885MAPT 1182/4885MEN1 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.