Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 10/20 | 0.45 |
| ▸ | MMP9 | P14780 | 10/20 | 0.45 |
| ▸ | MMP8 | P22894 | 9/20 | 0.45 |
| ▸ | MMP13 | P45452 | 9/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652641 | 0.83 | MMP2 (0.47) | MMP2MMP9MMP8MMP13KEAP1 | |
| SCHEMBL6076540 | 0.82 | KEAP1 (0.41) | MMP2MMP9MMP13KEAP1NFE2L2 | |
| SCHEMBL7089280 | 0.82 | MMP2 (0.59) | MMP2MMP9MMP8MMP13KEAP1 | |
| SCHEMBL7089279 | 0.82 | MMP2 (0.59) | MMP2MMP9MMP8MMP13KEAP1 | |
| SCHEMBL6498314 | 0.80 | ADAMTS4 (0.47) | KMT2AMEN1MMP2MMP9MMP8 | |
| SCHEMBL5451163 | 0.79 | TAS2R14 (0.64) | MMP2MMP9MMP8MMP13BMP1 | |
| SCHEMBL7387786 | 0.79 | KEAP1 (0.38) | MMP2MMP9MMP13KEAP1NFE2L2 | |
| SCHEMBL11956143 | 0.79 | BMP1 (0.54) | MMP2MMP9MMP8MMP13BMP1 | |
| SCHEMBL5463131 | 0.79 | BMP1 (0.54) | MMP2MMP9MMP8MMP13BMP1 | |
| SCHEMBL6388691 | 0.78 | MMP2 (0.51) | MMP2MMP9MMP8MMP13BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252439-A1 | CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE AGENTS FOR BORON NEUTRON CAPTURE THERAPY | LOYOLA UNIVERSITY OF CHICAGO (US) | 2020-12-17 | — | — | WO | disclosed |