Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147351 | 0.80 | TRPA1 (0.37) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL11741027 | 0.79 | MYC (0.48) | TRPA1ATMMYCCA1CA2 | |
| SCHEMBL7762823 | 0.77 | DHFR (0.47) | CA1CA2CA9CYP1A2CYP2A6 | |
| SCHEMBL18039125 | 0.76 | ALDH1A1 (0.40) | MYCMAPT | |
| SCHEMBL9275545 | 0.74 | TRPA1 (0.32) | TRPA1ATM | |
| SCHEMBL6699053 | 0.74 | TRPA1 (0.38) | TRPA1ATMCA1CA2CA7 | |
| SCHEMBL7450369 | 0.73 | MYC (0.32) | TRPA1ATMMYCP2RX7 | |
| SCHEMBL2320148 | 0.72 | PLA2G7 (0.36) | CYP1A2 | |
| SCHEMBL9004948 | 0.72 | HSD11B1 (0.44) | TRPA1PDK2 | |
| SCHEMBL125358 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830385-A1 | HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS | W.R. Grace & Co.-Conn. (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996013531-A1 | PREPARATION OF MODIFIED POLYOLEFIN CATALYSTS AND IN SITU PREPARATION OF SUPPORTED METALLOCENE AND ZIEGLER-NATTA/METALLOCENE POLYOLEFIN CATALYSTS | W.R. GRACE & CO.-CONN. (US) | 1996-05-09 | — | — | WO | claimed |
| EP-2407514-B1 | REINFORCED POLYESTER RESIN COMPOSITION | ADEKA CORP (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-9249267-B2 | Resin-additive masterbatch | ADEKA CORPORATION (JP) | 2016-02-02 | — | — | US | disclosed |
| EP-2077298-B1 | POLYESTER RESIN COMPOSITION | ADEKA CORP (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-8829084-B2 | Reinforced polyester resin composition | ADEKA CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| EP-2578620-A1 | RESIN-ADDITIVE MASTERBATCH | Adeka Corporation (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-20130065994-A1 | RESIN-ADDITIVE MASTERBATCH | ADEKA CORPORATION (JP) | 2013-03-14 | — | — | US | disclosed |
| EP-2022826-B1 | POLYESTER RESIN COMPOSITION | ADEKA CORP (JP) | 2012-05-16 | — | — | EP | disclosed |
| EP-2407514-A1 | REINFORCED POLYESTER RESIN COMPOSITION | Adeka Corporation (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20120004363-A1 | REINFORCED POLYESTER RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2012-01-05 | — | — | US | disclosed |
| US-20110034714-A1 | METAL COMPLEX COMPOUND, CANCER THERAPEUTIC AGENT COMPOSITION CONTAINING THE METAL COMPLEX COMPOUND AS AN ACTIVE INGREDIENT, AND INTERMEDIATE FOR THE METAL COMPLEX COMPOUND | EKIMOTO HISAO | 2011-02-10 | — | — | US | disclosed |
| US-20110015319-A1 | POLYESTER RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20100113710-A1 | POLYESTER RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2177525-A1 | METAL COMPLEX COMPOUND, CANCER THERAPEUTIC COMPOSITION COMPRISING THE METAL COMPLEX COMPOUND AS ACTIVE INGREDIENT, AND INTERMEDIATE FOR PRODUCTION OF THE METAL COMPLEX COMPOUND | TMRC Co., Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |
| EP-2077298-A1 | POLYESTER RESIN COMPOSITION | Adeka Corporation (JP) | 2009-07-08 | — | — | EP | disclosed |
| EP-2022826-A1 | POLYESTER RESIN COMPOSITION | Adeka Corporation (JP) | 2009-02-11 | — | — | EP | disclosed |
| EP-0830392-A1 | SUPPORTED CATALYST COMPOSITION FOR POLYMERIZATION OF OLEFINS | W.R. Grace & Co.-Conn. (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0830385-A1 | HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS | W.R. Grace & Co.-Conn. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040804-A1 | SUPPORTED CATALYST COMPOSITION FOR POLYMERIZATION OF OLEFINS | W.R. GRACE & CO.-CONN. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034714-A1 | METAL COMPLEX COMPOUND, CANCER THERAPEUTIC AGENT COMPOSITION CONTAINING THE METAL COMPLEX COMPOUND AS AN ACTIVE INGREDIENT, AND INTERMEDIATE FOR THE METAL COMPLEX COMPOUND | NR3C2, NR3C1, MC5R | TRPA1 333/4885ATM 1531/4885MYC 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.