SCHEMBL227931

SCHEMBL227931

CC(C)(C)c1[c]cc(C(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
LMNA P02545 1/20 0.39
TYR P14679 1/20 0.39
ALDH1A1 P00352 5/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KIF11 P52732 2/20 0.33
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC1 Q13547 1/20 0.31
SLC22A2 O15244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL905508 0.84 KIF11 (0.36) TSHRLMNATYRALDH1A1KIF11
SCHEMBL956938 0.75 TSHR (0.40) TSHRTDP1ACHE
SCHEMBL1550638 0.75 TSHR (0.46) TSHRLMNATYRALDH1A1HPGD
SCHEMBL25227526 0.73 POLB (0.39) TSHRLMNATYRALDH1A1HPGD
SCHEMBL1639237 0.73 LMNA (0.48) TSHRLMNATYRALDH1A1HPGD
SCHEMBL16166891 0.73 ACHE (0.31) ACHE
SCHEMBL6225432 0.73 TSHR (0.39) TSHRLMNATYRALDH1A1HPGD
SCHEMBL17262489 0.73 TSHR (0.39) TSHRLMNATYRALDH1A1HPGD
SCHEMBL7044344 0.73 CYP2A6 (0.32) ALDH1A1
SCHEMBL11798351 0.73 TSHR (0.39) TSHRLMNATYRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 825 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-115010839-B Amine-containing bisphenol tetradentate ligand fourth subgroup metal complex catalyst system and application thereof 吉林大学 2023-06-20 CN claimed
CN-114716585-B Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2023-02-28 CN claimed
CN-112830989-B Long-chain branched ethylene propylene rubber and preparation method thereof 北京引发科技有限公司 2022-07-29 CN claimed
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same LG CHEM, LTD. (KR) 2021-10-19 US claimed
CN-112830989-A Long-chain branched ethylene propylene rubber and preparation method thereof 北京引发科技有限公司 2021-05-25 CN claimed
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-01-30 US claimed
US-20190161514-A1 AZASTEROIDS FOR TREATMENT OF TUBERCULOSIS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2019-05-30 US claimed
CN-109790200-A For treating the azasteroid of tuberculosis 纽约州立大学研究基金会 2019-05-21 CN claimed
US-9932423-B2 Hydrogenation of annulated cyclopentadienyl metal complexes and metallocene catalysts comprising such EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-04-03 US claimed
EP-0805826-A2 ALPHA-OLEFINS AND OLEFIN POLYMERS AND PROCESSES THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-12 EP claimed
US-5650513-A Process for preparing perylene-3,4-dicarboxylic acid derivatives, the derivatives thus prepared and their use CIBA-GEIGY CORPORATION (US) 1997-07-22 US claimed
EP-0596553-B1 Catalyst composition for alkene oligomerisation and co-oligomerisation SHELL INT RESEARCH (NL) 1997-05-07 EP claimed
WO-1996023010-A2 α-OLEFINS AND OLEFIN POLYMERS AND PROCESSES THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-01 WO claimed
EP-0711812-A1 Method of preparation of perylene imides, novel di-, tri-, and tetrachromophore perylene dyestuffs and their utilization CIBA-GEIGY AG (CH) 1996-05-15 EP claimed
US-5508137-A REACTING A PERYLENE-3,4:9,10-TETRACARBOXYLIC MONOANHYDRIDE MONOIMIDE WITH A PRIMARY DIAMINE; FLUORESCENT DYE IN CHEMILUMINESCENCE SYSTEMS CIBA-GEIGY CORPORATION (US) 1996-04-16 US claimed
EP-0657436-A2 Process for the preparation of perylene-3,4-dicarboxylic acid derivatives, the compounds prepared according to this process and their use CIBA-GEIGY AG (CH) 1995-06-14 EP claimed
EP-0638613-A1 Perylene amidine-imide dyes, a process for their production and their use CIBA-GEIGY AG (CH) 1995-02-15 EP claimed
EP-0596553-A2 Catalyst composition for alkene oligomerisation and co-oligomerisation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1994-05-11 EP claimed
US-4845223-A FLUORESCENT PERYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 1989-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME ASIC1, PPA1, ATP6AP1 TSHR 3936/4885LMNA 4181/4885TYR 387/4885
US-20190161514-A1 AZASTEROIDS FOR TREATMENT OF TUBERCULOSIS CYP51A1, HSD17B13, HSD17B1 TSHR 914/4885LMNA 2730/4885TYR 4727/4885
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same ASIC1, PPA1, ATP6AP1 TSHR 3936/4885LMNA 4181/4885TYR 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.