Sugi Predict

Sugi Predict / Compounds / SCHEMBL48352

SCHEMBL48352

SCHEMBL48352

O=C(CCl)N1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.56
▸ ATM Q13315 1/20 0.54
▸ LMNA P02545 1/20 0.53
▸ SMN1; SMN2 Q16637 3/20 0.52
▸ POLB P06746 2/20 0.52
▸ HTT P42858 2/20 0.52
▸ GAA P10253 1/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ HPGD P15428 2/20 0.43
▸ TSHR P16473 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229257 1.00 ALDH1A1 (0.56) ALDH1A1ATMLMNASMN1; SMN2POLB
SCHEMBL227972 1.00 ALDH1A1 (0.56) ALDH1A1ATMLMNASMN1; SMN2POLB
SCHEMBL69354 0.97 — —
SCHEMBL224023 0.92 — —
SCHEMBL24693081 0.87 CA2 (0.50) ALDH1A1ATMLMNASMN1; SMN2POLB
SCHEMBL11742016 0.87 L3MBTL1 (0.52) ALDH1A1ATMLMNASMN1; SMN2POLB
SCHEMBL9279972 0.86 ALDH1A1 (0.64) ALDH1A1LMNASMN1; SMN2POLBHTT
SCHEMBL11844730 0.86 — —
SCHEMBL8978116 0.86 ALDH1A1 (0.64) ALDH1A1LMNASMN1; SMN2POLBHTT
SCHEMBL22481550 0.82 HPGD (0.62) ALDH1A1ATMLMNASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874601-A 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof 山东大学 2025-04-25 — — CN claimed
US-20250368608-A1 SELECTIVE HDAC6 INHIBITOR ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2025-12-04 — — US disclosed
US-12472166-B2 Inhibition of mycobacterial type VII secretion STICHTING VUMC (NL) 2025-11-18 — — US disclosed
US-20250250283-A1 COMPOUND CAPABLE OF REGULATING AND CONTROLLING ACTIVITY OF 15-PGDH, AND PREPARATION METHOD THEREFOR SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2025-08-07 — — US disclosed
US-20250243217-A1 COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-07-31 — — US disclosed
US-20250206745-A1 PYRROLOPYRIDAZINE DERIVATIVES AND RELATED USES NODTHERA LTD (GB) 2025-06-26 — — US disclosed
EP-4543446-A1 SUBSTITUTED FUSED BICYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT Alkermes, Inc. (US) 2025-04-30 — — EP disclosed
CN-119874601-A 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof 山东大学 2025-04-25 — — CN disclosed
CN-119768169-A Substituted fused bicyclic compounds and related methods of treatment 阿尔克姆斯有限公司 2025-04-04 — — CN disclosed
CN-119285617-A 1,3, 5-Trisubstituted indole derivatives and use thereof 沈阳药科大学 2025-01-10 — — CN disclosed
US-3946044-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-03-23 — — US disclosed
US-3946043-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-03-23 — — US disclosed
US-3944410-A Substituted oxadiazolidine dione herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-03-16 — — US disclosed
US-3942972-A Dioxolane substituted α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-03-09 — — US disclosed
US-3941580-A N,N-BIS(2-METHOXY-3,6-DICHLORO-BENZOYL-OXYALKYL) ANILINES VELSICOL CHEMICAL CORPORATION (US) 1976-03-02 — — US disclosed
US-3940259-A Dioxane substituted-α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-02-24 — — US disclosed
US-3933839-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-20 — — US disclosed
US-3932438-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-13 — — US disclosed
US-3932410-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-13 — — US disclosed
US-3931209-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368608-A1 SELECTIVE HDAC6 INHIBITOR HDAC6, HDAC3, HDAC1 ALDH1A1 3394/4885ATM 3211/4885LMNA 4049/4885
US-20250206745-A1 PYRROLOPYRIDAZINE DERIVATIVES AND RELATED USES IL1B, NLRP3, NLRP1 ALDH1A1 226/4885ATM 2361/4885LMNA 3535/4885
US-12472166-B2 Inhibition of mycobacterial type VII secretion CFTR, ABCB11, ABCC2 ALDH1A1 1733/4885ATM 3743/4885LMNA 2859/4885
US-20250243217-A1 COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY HPGD, GCDH, HPGDS ALDH1A1 126/4885ATM 3970/4885LMNA 1481/4885
US-20250250283-A1 COMPOUND CAPABLE OF REGULATING AND CONTROLLING ACTIVITY OF 15-PGDH, AND PREPARATION METHOD THEREFOR CYP11B1, CYP51A1, CYP11B2 ALDH1A1 242/4885ATM 4700/4885LMNA 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.