Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29235924 | 0.82 | GABRA1 (0.50) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL2750595 | 0.82 | CYP1A2 (0.38) | CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL14877302 | 0.80 | GABRA1 (0.60) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL28268413 | 0.78 | GABRA1 (0.55) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL28251645 | 0.76 | ALDH1A1 (0.37) | CA2ALDH1A1TSHR | |
| SCHEMBL12597782 | 0.75 | GABRA1 (0.43) | GABRA1GABRB2CA2 | |
| SCHEMBL28311512 | 0.73 | SMN1; SMN2 (0.43) | CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL2280822 | 0.71 | GABRA1 (0.43) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL1160034 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL2282082 | 0.71 | TRPA1 (0.41) | GABRA1GABRB2CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | GABRA1 3242/4885GABRB2 3138/4885CA2 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.