Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.46 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837119 | 0.93 | MAPT (0.45) | MAPTEPHX2NNMTL3MBTL1GRN | |
| SCHEMBL13875908 | 0.83 | MAPT (0.68) | MAPTNNMTL3MBTL1 | |
| SCHEMBL26172916 | 0.82 | OPRM1 (0.44) | — | |
| SCHEMBL13875906 | 0.82 | NNMT (0.64) | MAPTNNMTL3MBTL1KCNH2 | |
| SCHEMBL22968740 | 0.80 | LTK (0.35) | EPHX2NNMTGRNSORT1IDO1 | |
| SCHEMBL13875896 | 0.79 | L3MBTL1 (0.70) | MAPTEPHX2L3MBTL1SCN9A | |
| SCHEMBL19481639 | 0.79 | NNMT (0.44) | MAPTNNMTKCNH2 | |
| SCHEMBL22837053 | 0.78 | KCNK3 (0.35) | MAPTEPHX2IDO1 | |
| SCHEMBL22837004 | 0.78 | L3MBTL1 (0.49) | MAPTL3MBTL1 | |
| SCHEMBL13875951 | 0.75 | GAA (0.52) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667667-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-11667667-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-20210040140-A1 | Steroid Derivative FXR Agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-02-11 | — | — | US | disclosed |
| US-10875888-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667667-B2 | Steroid derivative FXR agonist | NR1H4, SLC10A1, FXR1 | MAPT 236/4885EPHX2 1825/4885NNMT 2673/4885 |
| US-20210040140-A1 | Steroid Derivative FXR Agonist | NR1H4, SLC10A1, FXR1 | MAPT 236/4885EPHX2 1825/4885NNMT 2673/4885 |
| US-10875888-B2 | Steroid derivative FXR agonist | NR1H4, SLC10A1, FXR1 | MAPT 236/4885EPHX2 1825/4885NNMT 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.