Sugi Predict

Sugi Predict / Compounds / SCHEMBL18339258

SCHEMBL18339258

SCHEMBL18339258

CC1(C)C2CC=C(C=CO)C1C2

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.52
▸ TSHR P16473 2/20 0.52
▸ ALOX12 P18054 4/20 0.50
▸ ALDH1A1 P00352 5/20 0.49
▸ KDM4E B2RXH2 3/20 0.49
▸ LMNA P02545 3/20 0.44
▸ HPGD P15428 1/20 0.43
▸ CRHBP P24387 1/20 0.43
▸ CRHR2 Q13324 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ HTT P42858 2/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ CXCR3 P49682 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18339257 1.00 MAPK1 (0.52) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL5297079 0.85 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL14321805 0.78 MAPK1 (0.47) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL14321808 0.78 MAPK1 (0.47) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL228374 0.78 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL11074361 0.78 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL1300746 0.78 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL5391946 0.78 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL13057758 0.72 ALDH1A1 (0.42) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL13057760 0.72 ALDH1A1 (0.42) MAPK1TSHRALOX12ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633370-A1 CO-FORMULATION COMPOSITION ACTION PIN (FR) 2025-10-22 — — EP claimed
WO-2024126767-A1 CO-FORMULATION COMPOSITION ACTION PIN (FR) 2024-06-20 — — WO claimed
EP-4593595-A1 USE OF RESIN ACIDS AS DEFENSE GENE INDUCERS FOR BIOTIC STRESS IN PLANTS ACTION PIN (FR) 2025-08-06 — — EP disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
WO-2024068671-A1 USE OF RESIN ACIDS AS DEFENSE GENE INDUCERS FOR BIOTIC STRESS IN PLANTS ACTION PIN (FR) 2024-04-04 — — WO disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 — — US disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 — — EP disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 — — US disclosed
EP-3368542-A2 HIGH INTENSITY SWEETENERS Senomyx, Inc. (US) 2018-09-05 — — EP disclosed
EP-3356356-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2018-08-08 — — EP disclosed
US-9732071-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2017-08-15 — — US disclosed
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent SENOMYX INC (US) 2017-05-25 — — US disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 — — WO disclosed
US-20170119032-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED 2017-05-04 — — US disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 — — US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 — — US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MAPK1 1556/4885TSHR 3246/4885ALOX12 3414/4885
US-20170119032-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MAPK1 1556/4885TSHR 3246/4885ALOX12 3414/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 MAPK1 1594/4885TSHR 2120/4885ALOX12 3016/4885
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 MAPK1 1501/4885TSHR 2580/4885ALOX12 3321/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 MAPK1 1556/4885TSHR 3246/4885ALOX12 3414/4885
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent TAS2R8, TAS2R45, TAS2R40 MAPK1 2740/4885TSHR 2694/4885ALOX12 966/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D MAPK1 864/4885TSHR 2063/4885ALOX12 2080/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MAPK1 1556/4885TSHR 3246/4885ALOX12 3414/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 MAPK1 1556/4885TSHR 3246/4885ALOX12 3414/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 MAPK1 1875/4885TSHR 2031/4885ALOX12 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.