SCHEMBL228422

SCHEMBL228422

CC1=C(N)C(=O)c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.56
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
ALDH1A1 P00352 5/20 0.56
CDC25A P30304 4/20 0.56
MAPT P10636 3/20 0.56
POLB P06746 2/20 0.56
NSD2 O96028 2/20 0.56
AURKA O14965 1/20 0.56
AURKB Q96GD4 1/20 0.56
S100A4 P26447 4/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAP2K7 O14733 2/20 0.48
MAOA P21397 3/20 0.48
ADORA2A P29274 2/20 0.48
FGR P09769 1/20 0.48
PIM1 P11309 1/20 0.48
CSNK1A1 P48729 1/20 0.48
CSNK1D P48730 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859810 1.00 CDC25B (0.56) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL25706387 0.84 RAB9A (0.52) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL11573761 0.83 S100A4 (0.50) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL29563346 0.82 RAB9A (0.68) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL571026 0.82 CDC25B (0.68) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL1510327 0.82 RAB9A (0.68) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL29941466 0.82 CDC25B (0.68) CDC25BNPC1RAB9AALDH1A1CDC25A
Water SCHEMBL8664586 0.79 CDC25B (0.65) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL18059577 0.79 ALDH1A1 (0.46) CDC25BNPC1RAB9AALDH1A1CDC25A
SCHEMBL15491792 0.77 CDC25B (0.62) CDC25BNPC1RAB9AALDH1A1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866692-A1 USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK LABORATOIRE INNOTHERA Société Anonyme (FR) 1998-09-30 EP claimed
WO-1997021432-A1 USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK LABORATOIRE INNOTHERA, S.A. (FR) 1997-06-19 WO claimed
EP-4333135-A1 LIPOLYSIS DEVICE, LIPOLYSIS METHOD, AND ELECTRIC POWER GENERATION METHOD Murata Manufacturing Co., Ltd. (JP) 2024-03-06 EP disclosed
US-20230398008-A1 LIPOLYSIS DEVICE, LIPOLYSIS METHOD, AND ELECTRIC POWER GENERATION METHOD MURATA MANUFACTURING CO., LTD. (JP) 2023-12-14 US disclosed
CN-116941078-A Fat decomposition device, fat decomposition method, and power generation method 株式会社村田制作所 2023-10-24 CN disclosed
WO-2022230464-A1 LIPOLYSIS DEVICE, LIPOLYSIS METHOD, AND ELECTRIC POWER GENERATION METHOD 株式会社村田製作所 2022-11-03 WO disclosed
US-20220128562-A1 BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF UNIVERSITY OF KANSAS 2022-04-28 US disclosed
US-10391070-B2 Compositions and methods for treating neurological diseases or injury MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2019-08-27 US disclosed
US-10391070-B2 Compositions and methods for treating neurological diseases or injury MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2019-08-27 US disclosed
US-20180185306-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2018-07-05 US disclosed
US-20180185306-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2018-07-05 US disclosed
EP-2157652-A1 FUEL CELL AND ELECTRONIC EQUIPMENT Sony Corporation (JP) 2010-02-24 EP disclosed
EP-2131437-A1 ENZYME IMMOBILIZED ELECTRODE, FUEL CELL, ELECTRONIC EQUIPMENT, ENZYME REACTION UTILIZATION APPARATUS, AND ENZYME IMMOBILIZED BASE Sony Corporation (JP) 2009-12-09 EP disclosed
US-20090053579-A1 NOVEL POWER SUPPLY DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SONY CORPORATION (JP) 2009-02-26 US disclosed
EP-2028712-A2 Biofuel cell, method for producing the same, electronic apparatus, enzyme-immobilized electrode, and method for producing the same Sony Corporation (JP) 2009-02-25 EP disclosed
US-20090047567-A1 Biofuel cell, method for producing the same, electronic apparatus, enzyme-immobilized electrode, and method for producing the same SONY CORPORATION (JP) 2009-02-19 US disclosed
US-20090047550-A1 METHOD FOR MANUFACTURING FUEL CELL, FUEL CELL, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2009-02-19 US disclosed
US-20080280184-A1 FUEL CELL, METHOD FOR MANUFACTURING FUEL CELL, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2008-11-13 US disclosed
EP-0866692-A1 USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK LABORATOIRE INNOTHERA Société Anonyme (FR) 1998-09-30 EP disclosed
WO-1997021432-A1 USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK LABORATOIRE INNOTHERA, S.A. (FR) 1997-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10391070-B2 Compositions and methods for treating neurological diseases or injury PROC, GLS, NLN CDC25B 3726/4885NPC1 1022/4885RAB9A 1436/4885
US-20180185306-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY PROC, GLS, NLN CDC25B 3726/4885NPC1 1022/4885RAB9A 1436/4885
US-20220128562-A1 BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF NQO1, KEAP1, NFE2L2 CDC25B 846/4885NPC1 3149/4885RAB9A 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.