Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.46 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | CCR8 | P51685 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864242 | 0.81 | NSD2 (0.34) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL22864223 | 0.78 | ALDH1A1 (0.42) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL22864232 | 0.78 | HDAC6 (0.46) | PSMD14COPS5CCR1CCR8ADRA1A | |
| SCHEMBL22864243 | 0.76 | HTR5A (0.49) | L3MBTL1HTTALDH1A1POLBKDM4E | |
| SCHEMBL9828866 | 0.75 | PSMD14 (0.58) | PSMD14COPS5CCR1CCR8HTR1A | |
| SCHEMBL3272867 | 0.75 | PSMD14 (0.58) | PSMD14COPS5CCR1CCR8HTR1A | |
| SCHEMBL22864155 | 0.74 | SLC40A1 (0.43) | L3MBTL1KDM4EKMT2APAX8 | |
| SCHEMBL22864222 | 0.74 | ALDH1A1 (0.34) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL16938252 | 0.73 | PSMD14 (0.56) | PSMD14COPS5CCR1CCR8HTR1A | |
| SCHEMBL22493402 | 0.72 | P2RX7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003161-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |