Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9927884 | 0.96 | MGLL (0.52) | FAAHMGLLLMNAMAPTALOX15 | |
| SCHEMBL22919640 | 0.92 | NAAA (0.44) | PRKCALMNAMAPTNPSR1 | |
| SCHEMBL7278773 | 0.92 | NAAA (0.44) | PRKCALMNAMAPTNPSR1 | |
| SCHEMBL21261912 | 0.90 | LPAR2 (0.40) | FAAHMGLLLMNAMAPTALOX15 | |
| SCHEMBL2037671 | 0.90 | NAAA (0.42) | PRKCALMNA | |
| SCHEMBL27093698 | 0.89 | FAAH (0.38) | FAAHMGLLEPHX2PRKCA | |
| SCHEMBL13114348 | 0.88 | MGLL (0.47) | FAAHMGLLLMNAMAPTALOX15 | |
| Bicarbonate SCHEMBL27875196 | 0.87 | NAAA (0.40) | PRKCALMNA | |
| SCHEMBL12903327 | 0.86 | NAAA (0.40) | PRKCALMNAMAPT | |
| SCHEMBL13541624 | 0.85 | ALDH1A1 (0.42) | LMNACYP1A2POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148595-A1 | GABA-LINKED ANTHRACYCLINE-LIPID CONJUGATES | LUITPOLD PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120148595-A1 | GABA-LINKED ANTHRACYCLINE-LIPID CONJUGATES | LUITPOLD PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| WO-2010104585-A1 | GABA-LINKED ANTHRACYCLINE-LIPID CONJUGATES | LUITPOLD PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148595-A1 | GABA-LINKED ANTHRACYCLINE-LIPID CONJUGATES | GABRB2, GABRB3, GABRB1 | FAAH 323/4885MGLL 337/4885EPHX2 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.