SCHEMBL229044

SCHEMBL229044

N[C@@H](Cc1ccc(O)nc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.61
HSD17B10 Q99714 2/20 0.58
PTGS1 P23219 3/20 0.56
ALOX15 P16050 3/20 0.56
HIF1A Q16665 3/20 0.56
KDM4E B2RXH2 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
USP2 O75604 1/20 0.56
EGFR P00533 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
HTR2A P28223 1/20 0.56
PTGS2 P35354 1/20 0.56
RECQL P46063 1/20 0.56
PKM P14618 2/20 0.55
ALPI P09923 1/20 0.55
XIAP P98170 1/20 0.55
TYR P14679 5/20 0.47
TPH1 P17752 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19704241 1.00 SLC7A5 (0.61) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL18375252 0.86 SLC7A5 (0.43) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL25578551 0.86 SLC7A5 (0.43) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL20369611 0.86 SLC7A5 (0.43) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL26008176 0.83 CPB2 (0.63) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL4629770 0.83 CPB2 (0.63) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL15314368 0.83 CPB2 (0.63) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL25355779 0.81 P4HTM (0.57) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL2073432 0.81 HSD17B10 (0.57) SLC7A5HSD17B10PTGS1ALOX15HIF1A
SCHEMBL5291267 0.81 HSD17B10 (0.57) SLC7A5HSD17B10PTGS1ALOX15HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9844509-B2 High throughput fabrication of nanoparticles PFIZER INC. (US) 2017-12-19 US claimed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US disclosed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
US-20230174460-A1 AFMT ANALOGS AND THEIR USE IN METHODS OF TREATING PARKINSON'S DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2023-06-08 US disclosed
WO-2021216781-A1 AFMT ANALOGS AND THEIR USE IN METHODS OF TREATING PARKINSON'S DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-10-28 WO disclosed
WO-2020194563-A1 AGENT FOR PREVENTING OR IMPROVING SYMPTOMS OR DISEASE CAUSED BY PHENOLS 国立大学法人東北大学 2020-10-01 WO disclosed
EP-2793027-B1 Unnatural reactive amino acid genetic code additions SCRIPPS RESEARCH INST (US) 2019-11-13 EP disclosed
US-9797908-B2 Unnatural reactive amino acid genetic code additions THE SCRIPPS RESEARCH INSTITUTE (US) 2017-10-24 US disclosed
US-9580721-B2 Expanding the eukaryotic genetic code The Scripps Reserach Institute (US) 2017-02-28 US disclosed
US-20080176277-A1 Expanding the eukaryotic genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2008-07-24 US disclosed
US-20070166791-A1 Expanding the eukaryotic genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2007-07-19 US disclosed
US-20070154952-A1 Expanding the eukaryotic genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2007-07-05 US disclosed
US-20060246509-A1 protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors THE SCRIPPS RESEARCH INSTITUTE 2006-11-02 US disclosed
EP-1636340-A2 UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS The Scripps Research Institute (US) 2006-03-22 EP disclosed
EP-1613735-A2 EXPANDING THE EUKARYOTIC GENETIC CODE The Scripps Research Institute (US) 2006-01-11 EP disclosed
US-20050009049-A1 Expanding the eukaryotic genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2005-01-13 US disclosed
WO-2005003294-A2 UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2005-01-13 WO disclosed
US-20040265952-A1 protein containing a modified amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug that carries an alkynyl or azido group; translation biochemistry in eukaryotic cells; gene expression inhibitors THE SCRIPPS RESEARCH INSTITUTE (US) 2004-12-30 US disclosed
WO-2004094593-A2 EXPANDING THE EUKARYOTIC GENETIC CODE THE SCRIPPS RESEARCH INSTITUTE (US) 2004-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154952-A1 Expanding the eukaryotic genetic code NSUN3, AARS1, TRMT1 SLC7A5 263/4885HSD17B10 1956/4885PTGS1 3470/4885
US-20050009049-A1 Expanding the eukaryotic genetic code NSUN3, AARS1, TRMT1 SLC7A5 263/4885HSD17B10 1956/4885PTGS1 3470/4885
US-20060246509-A1 protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors AARS1, ASNS, KARS1 SLC7A5 431/4885HSD17B10 2154/4885PTGS1 4151/4885
US-20230174460-A1 AFMT ANALOGS AND THEIR USE IN METHODS OF TREATING PARKINSON'S DISEASE PARK7, SNCA, RHOT2 SLC7A5 772/4885HSD17B10 2331/4885PTGS1 2147/4885
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof SSTR2, SSTR4, SSTR5 SLC7A5 286/4885HSD17B10 4794/4885PTGS1 4839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.