SCHEMBL22906103

SCHEMBL22906103

O=C(CCCC(=O)OCc1ccccc1)C[C@@H]1OC(CO)[C@@H](O[C@@H]2OC(CO)[C@H](O)C(O)CC2O)C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.44
SLC6A2 P23975 2/20 0.39
HRAS P01112 1/20 0.39
PTPN1 P18031 1/20 0.35
SLC5A1 P13866 1/20 0.35
SLC5A2 P31639 1/20 0.35
FGF1 P05230 1/20 0.35
FGF2 P09038 1/20 0.35
VEGFA P15692 1/20 0.35
HPSE Q9Y251 1/20 0.35
SYNJ2 O15056 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ABL1 P00519 1/20 0.35
ALPL P05186 1/20 0.35
POLB P06746 1/20 0.35
ALPI P09923 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
ALPG P10696 1/20 0.35
PABPC1 P11940 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391509 0.90 LGALS8 (0.48) LGALS8SLC6A2HRASSLC5A1SLC5A2
SCHEMBL21391539 0.90 LGALS8 (0.48) LGALS8SLC6A2HRASSLC5A1SLC5A2
SCHEMBL22906135 0.90 LGALS8 (0.48) LGALS8SLC6A2HRASSLC5A1SLC5A2
SCHEMBL22906104 0.85 LGALS8 (0.37) LGALS8FGF1KDM4EPOLB
SCHEMBL21391541 0.85 LGALS8 (0.49) LGALS8SLC6A2HRASSLC5A1SLC5A2
SCHEMBL21391503 0.75 AMY1A (0.35) LGALS8PTPN1KDM4EPOLBMAPT
SCHEMBL21391533 0.74 LGALS3 (0.47) LGALS8KDM4EPOLB
SCHEMBL10136110 0.71 LGALS8 (0.51) LGALS8SLC6A2HRASPTPN1FGF1
SCHEMBL19500446 0.70 LGALS8 (0.52) LGALS8SYNJ2KDM4EABL1ALPL
SCHEMBL19509830 0.70 LGALS8 (0.52) LGALS8SYNJ2KDM4EABL1ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210017211-A1 OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2021-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017211-A1 OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES OSTC, FUT6, FUT5 LGALS8 253/4885SLC6A2 2690/4885HRAS 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.