SCHEMBL22906243

SCHEMBL22906243

Cc1nn(C)c(=O)c(-c2c(F)ccc(Cl)c2CCc2ccc(-n3cncn3)cc2)c1O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
CYP11B2 P19099 1/20 0.33
BRS3 P32247 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSP90AA1 P07900 1/20 0.32
HTT P42858 1/20 0.32
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
AR P10275 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22906276 0.86 RAB9A (0.33) RAB9ARXFP1BRS3MAPTSMN1; SMN2
SCHEMBL28800360 0.86 RAB9A (0.34) RAB9ARXFP1BRS3DPP4DPP8
SCHEMBL25184826 0.86 CHRM1 (0.40) BRS3MAPTSMN1; SMN2ARKDM4E
SCHEMBL30389045 0.86 CHRM1 (0.40) BRS3MAPTSMN1; SMN2ARKDM4E
SCHEMBL22084636 0.86 LMNA (0.36) RAB9AMAPTSMN1; SMN2
SCHEMBL25184315 0.86 MAPT (0.32) MAPTHTTAR
SCHEMBL30389363 0.86 MAPT (0.32) MAPTHTTAR
SCHEMBL22031854 0.85 CYP1A2 (0.38) MAPTSMN1; SMN2AR
SCHEMBL25201217 0.83 MAPT (0.34) MAPT
SCHEMBL30389235 0.83 MAPT (0.34) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4371986-B1 SUBSTITUTED PYRIDAZINONES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP disclosed
US-12540120-B2 Herbicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2026-02-03 US disclosed
US-20250304990-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 US disclosed
CN-114555563-B Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-11-15 CN disclosed
EP-3999494-B1 SUBSTITUTED PYRIDAZINONES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-09-11 EP disclosed
CN-118265781-A Herbicide resistance 先正达农作物保护股份公司 2024-06-28 CN disclosed
CN-118108674-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-31 CN disclosed
CN-118084803-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN disclosed
CN-118084802-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN disclosed
EP-4371986-A2 SUBSTITUTED PYRIDAZINONES AS HERBICIDES Syngenta Crop Protection AG (CH) 2024-05-22 EP disclosed
EP-4357344-A2 SUBSTITUTED PYRIDAZINONES AS HERBICIDES Syngenta Crop Protection AG (CH) 2024-04-24 EP disclosed
WO-2023083972-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2023-05-19 WO disclosed
US-20220281827-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-09-08 US disclosed
CN-114555563-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2022-05-27 CN disclosed
EP-3999494-A2 SUBSTITUTED PYRIDAZINONES AS HERBICIDES Syngenta Crop Protection AG (CH) 2022-05-25 EP disclosed
WO-2021009334-A2 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281827-A1 HERBICIDAL COMPOUNDS DDT, HPD, PGD RAB9A 4008/4885RXFP1 3165/4885CYP11B2 515/4885
US-12540120-B2 Herbicidal compounds CBR3, CBR1, HACL2 RAB9A 3760/4885RXFP1 2585/4885CYP11B2 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.