Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 3/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908423 | 0.87 | BTK (0.31) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22908536 | 0.85 | CYP2D6 (0.37) | MEN1KMT2AHTR4MAPTCYP2D6 | |
| SCHEMBL22908541 | 0.84 | LMNA (0.38) | MEN1KMT2A | |
| SCHEMBL22908447 | 0.82 | HTR4 (0.34) | HTR4 | |
| SCHEMBL22908427 | 0.82 | HTR4 (0.34) | HTR4 | |
| SCHEMBL22908534 | 0.82 | HTR1A (0.34) | — | |
| SCHEMBL22908540 | 0.81 | CYP2D6 (0.41) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22908552 | 0.81 | CYP3A4 (0.44) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22908535 | 0.80 | POLB (0.32) | — | |
| SCHEMBL22908538 | 0.80 | CCR8 (0.41) | MEN1KMT2ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |