Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912307 | 0.79 | NPC1 (0.33) | CSF1RPDE2AMAPK1MEN1LMNA | |
| SCHEMBL22912306 | 0.70 | L3MBTL1 (0.35) | SMN1; SMN2TDP1CSF1RMAPK1MEN1 | |
| SCHEMBL20985647 | 0.63 | SDHB (0.51) | — | |
| SCHEMBL22912212 | 0.61 | SDHB (0.46) | PDE2A | |
| SCHEMBL28307428 | 0.61 | DRD4 (0.30) | — | |
| SCHEMBL26313133 | 0.60 | SDHB (0.47) | TDP1MEN1KMT2A | |
| SCHEMBL23503845 | 0.59 | VCP (0.40) | SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL29976635 | 0.58 | TP53 (0.37) | SMN1; SMN2PDE2AMAPK1MEN1LMNA | |
| SCHEMBL19805988 | 0.57 | SDHB (0.53) | SMN1; SMN2PDE2AMAPK1LMNA | |
| SCHEMBL20985662 | 0.55 | SDHB (0.42) | PDE2AMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |