Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278773 | 1.00 | NAAA (0.44) | NAAAEPHX1TSHRALDH1A1LMNA | |
| SCHEMBL2037671 | 0.98 | NAAA (0.42) | NAAAEPHX1TSHRALDH1A1LMNA | |
| Bicarbonate SCHEMBL27875196 | 0.95 | NAAA (0.40) | NAAAEPHX1TSHRALDH1A1LMNA | |
| SCHEMBL12903327 | 0.94 | NAAA (0.40) | NAAAEPHX1TSHRALDH1A1LMNA | |
| SCHEMBL13541624 | 0.93 | ALDH1A1 (0.42) | NAAATSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL13748507 | 0.92 | ALOX12 (0.38) | NAAATSHRALDH1A1PRKCACYP3A4 | |
| SCHEMBL1949595 | 0.92 | ALOX12 (0.38) | NAAATSHRALDH1A1PRKCACYP3A4 | |
| SCHEMBL9927889 | 0.92 | FAAH (0.46) | LMNAPRKCANPSR1MAPT | |
| SCHEMBL5821258 | 0.91 | KMT2A (0.41) | NAAAEPHX1TSHRALDH1A1LMNA | |
| SCHEMBL863059 | 0.91 | KMT2A (0.41) | NAAAEPHX1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163934-A1 | BBB-PASSING LIPID LIGAND OF HETERO NUCLEIC ACID | NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3770257-A1 | BBB-PASSING LIPID LIGAND OF HETERO NUCLEIC ACID | National University Corporation Tokyo Medical and Dental University (JP) | 2021-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163934-A1 | BBB-PASSING LIPID LIGAND OF HETERO NUCLEIC ACID | LDLR, FABP7, APOB | NAAA 2139/4885EPHX1 1226/4885TSHR 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.