SCHEMBL29626977

SCHEMBL29626977

CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCOC(=O)c1ccccc1OC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
TSHR P16473 2/20 0.52
PTGS2 P35354 1/20 0.52
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
LPAR3 Q9UBY5 6/20 0.49
ENPP2 Q13822 3/20 0.49
LPAR1 Q92633 3/20 0.49
PRKCA P17252 3/20 0.49
LPAR2 Q9HBW0 2/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17539124 1.00 ALDH1A1 (0.55) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL19608786 0.91 PTGS2 (0.57) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL4728781 0.84 ALDH1A1 (0.72) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL4728775 0.84 ALDH1A1 (0.72) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL11314352 0.84 ALDH1A1 (0.72) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL4732320 0.84 ALDH1A1 (0.72) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL4730460 0.84 ALDH1A1 (0.72) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL27528077 0.83 TSHR (0.71) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL22470008 0.83 PRKCA (0.46) ALDH1A1LMNATSHRPTGS2TP53
SCHEMBL17498842 0.82 PTGS2 (0.59) ALDH1A1LMNATSHRPTGS2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2026-04-16 US disclosed
US-20250352510-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-11-20 US disclosed
US-20250213522-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-07-03 US disclosed
EP-4578865-A2 LYMPH DIRECTING PRODRUGS Monash University (AU) 2025-07-02 EP disclosed
EP-3180349-B1 LYMPH DIRECTING PRODRUGS AND THERAPEUTIC USES THEREOF UNIV MONASH (AU) 2025-03-12 EP disclosed
US-20220211664-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2022-07-07 US disclosed
US-11311512-B2 Lymph directing prodrugs MONASH UNIVERSITY (AU) 2022-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211664-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN ALDH1A1 1056/4885LMNA 3766/4885TSHR 3045/4885
US-11311512-B2 Lymph directing prodrugs LTA, ABCB11, LYN ALDH1A1 1056/4885LMNA 3766/4885TSHR 3045/4885
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MALT1, CES1, LIPA ALDH1A1 1086/4885LMNA 964/4885TSHR 1545/4885
US-20250213522-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN ALDH1A1 1056/4885LMNA 3766/4885TSHR 3045/4885
US-20250352510-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN ALDH1A1 1056/4885LMNA 3766/4885TSHR 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.