SCHEMBL22929888

SCHEMBL22929888

c1ccc2c(c1)-c1ccccc1-c1cc(-n3c4ccccc4c4ccccc43)ccc1-c1ccc(-c3ccnc(-c4ccc5c(c4)-c4ccccc4-c4ccccc4-c4ncccc4-5)n3)cc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
KMT2A Q03164 4/20 0.38
NPSR1 Q6W5P4 3/20 0.38
PTK2B Q14289 1/20 0.38
HTT P42858 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
POLB P06746 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
THRB P10828 1/20 0.36
PPP1CA P62136 1/20 0.36
RAB9A P51151 3/20 0.33
KDM4E B2RXH2 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 1/20 0.33
MCL1 Q07820 3/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22929960 0.90 TGFBR1 (0.35) MAPTKMT2ANPSR1CYP1A2CYP2C9
SCHEMBL22929956 0.90 MAPT (0.38) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL22929893 0.89 PTPRC (0.31) KDM4ECTSLPTPRCCTSSPTPN13
SCHEMBL22929959 0.86 PIM1 (0.32) KDM4EMCL1CTSLPTPRCCTSS
SCHEMBL22930027 0.85 KDM4E (0.41) MAPTKMT2AHTTTHRBKDM4E
SCHEMBL22929889 0.83 MAPT (0.38) MAPTKMT2ANPSR1PTK2BHTT
SCHEMBL22929904 0.81 KDM4E (0.42) KMT2AHTTTHRBKDM4ESMN1; SMN2
SCHEMBL22929955 0.81 ATM (0.35) MAPTKMT2ANPSR1HTTTHRB
SCHEMBL22929920 0.78 KDM4E (0.39) KMT2AHTTTHRBKDM4ESMN1; SMN2
SCHEMBL22929946 0.77 KDM4E (0.43) KDM4EALDH1A1CTSLPTPRCCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 MAPT 3767/4885KMT2A 2837/4885NPSR1 3214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.