SCHEMBL22929893

SCHEMBL22929893

c1ccc2c(c1)-c1ccccc1-c1cc(-n3c4ccccc4c4ccccc43)ccc1-c1ccc(-c3ncnc(-c4ccc5c(c4)-c4ccccc4-c4ccccc4-c4ncccc4-5)n3)cc1-2

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.31
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
PTPN13 Q12923 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22929888 0.89 MAPT (0.38) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22930027 0.87 KDM4E (0.41) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929960 0.85 TGFBR1 (0.35) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929959 0.83 PIM1 (0.32) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929904 0.83 KDM4E (0.42) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929954 0.83
SCHEMBL22929955 0.82 ATM (0.35) PTPRCKDM4EATML3MBTL1
SCHEMBL22930035 0.81 CYP11B2 (0.32) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929920 0.80 KDM4E (0.39) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL17297257 0.80 ATM (0.42) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 PTPRC 251/4885CTSL 4185/4885CTSS 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.