SCHEMBL22929959

SCHEMBL22929959

c1ccc2c(c1)-c1ccccc1-c1cc(-n3c4ccccc4c4ccccc43)ccc1-c1ccc(-c3cncc(-c4ccc5c(c4)-c4ccccc4-c4ccccc4-c4ncccc4-5)n3)cc1-2

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.32
PIM3 Q86V86 1/20 0.32
FEN1 P39748 1/20 0.32
TGFBR1 P36897 1/20 0.31
PTPRC P08575 2/20 0.31
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
PTPN13 Q12923 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MCL1 Q07820 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22929960 0.91 TGFBR1 (0.35) TGFBR1PTPRCCTSLCTSSPTPN13
SCHEMBL22929888 0.86 MAPT (0.38) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22930027 0.86 KDM4E (0.41) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929893 0.83 PTPRC (0.31) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929956 0.82 MAPT (0.38) TGFBR1KDM4EMCL1
SCHEMBL22929904 0.82 KDM4E (0.42) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL22929955 0.82 ATM (0.35) FEN1TGFBR1PTPRCGABRG2GABRB3
SCHEMBL22930035 0.80 CYP11B2 (0.32) PIM1TGFBR1PTPRCCTSLCTSS
SCHEMBL22929920 0.79 KDM4E (0.39) PTPRCCTSLCTSSPTPN13KDM4E
SCHEMBL20062489 0.78 KDM4E (0.34) PTPRCKDM4EATML3MBTL1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 PIM1 2282/4885PIM3 1800/4885FEN1 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.