SCHEMBL22929892

SCHEMBL22929892

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)-c1ccccc1-c1ccccc1-c1cc(-c3cccc(-c4ccc5c(c4)-c4ccccc4-c4ccccc4-c4ncccc4-5)c3)ccc1-2

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.34
TDO2 P48775 2/20 0.34
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
GRM5 P41594 4/20 0.33
CLK4 Q9HAZ1 1/20 0.33
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.32
CYP19A1 P11511 1/20 0.32
CYP17A1 P05093 1/20 0.32
PTGER4 P35408 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
MAOB P27338 1/20 0.31
KCNN4 O15554 1/20 0.31
KCNA5 P22460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22929961 0.93 FLT3 (0.31) FLT3TDO2DDB1CRBNGRM5
SCHEMBL22930034 0.85 PDK2 (0.37) FLT3
SCHEMBL22929891 0.85 PDK2 (0.37) FLT3
SCHEMBL22929955 0.85 ATM (0.35)
SCHEMBL22930035 0.85 CYP11B2 (0.32) CYP11B2
SCHEMBL22929924 0.83 ALDH1A1 (0.34)
SCHEMBL22930027 0.81 KDM4E (0.41)
SCHEMBL21928118 0.80 GABRA1 (0.38) TDO2DDB1CRBNGRM5CLK4
SCHEMBL21927254 0.80 METAP2 (0.36) DDB1CRBNGRM5CLK4PTGER4
SCHEMBL22929960 0.79 TGFBR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 FLT3 1713/4885TDO2 2655/4885DDB1 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.