Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.40 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290238 | 0.91 | SHBG (0.47) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL3232508 | 0.82 | CA2 (0.52) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL2172272 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL29387025 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL6015498 | 0.79 | CYP3A4 (0.51) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL11806573 | 0.79 | CA2 (0.48) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL30702410 | 0.78 | SHBG (0.55) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL11189634 | 0.78 | SHBG (0.46) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL8606013 | 0.78 | SHBG (0.55) | SHBGALDH1A1CYP3A4ALOX15HIF1A | |
| SCHEMBL767213 | 0.76 | SHBG (0.52) | SHBGALDH1A1CYP3A4ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | SHBG 3588/4885ALDH1A1 4653/4885CYP3A4 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.