SCHEMBL22940

SCHEMBL22940

C[C@](O)(C(=O)O)c1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRK1 P41145 1/20 0.42
KCNH2 Q12809 1/20 0.42
KCNN4 O15554 1/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
PDK1 Q15118 4/20 0.40
PDK2 Q15119 4/20 0.40
PDK3 Q15120 4/20 0.40
PDK4 Q16654 4/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
KIF11 P52732 1/20 0.39
CYP2C9 P11712 2/20 0.38
CYP1A2 P05177 1/20 0.38
HSD11B1 P28845 1/20 0.38
POLB P06746 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24542 1.00 HTR2A (0.42) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL30501925 0.82 KCNN4 (0.44) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL785777 0.82 KCNN4 (0.44) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL1417552 0.80 KCNN4 (0.42) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL1417550 0.80 KCNN4 (0.42) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL4838145 0.80 KCNN4 (0.42) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL31612950 0.79 LMNA (0.47) KCNN4ALDH1A1L3MBTL1PDK1PDK2
SCHEMBL31612951 0.79 LMNA (0.47) KCNN4ALDH1A1L3MBTL1PDK1PDK2
SCHEMBL4564870 0.79 KCNN4 (0.45) HTR2AHTR2CADRA1AOPRK1KCNH2
SCHEMBL2798675 0.79 CYP2C9 (0.50) HTR2AHTR2CADRA1AOPRK1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970112-B1 PHENYL CARBAMATE COMPOUND AND A COMPOSITION FOR PREVENTING OR TREATING A MEMORY LOSS-RELATED DISEASE COMPRISING THE SAME BIO PHARM SOLUTIONS CO LTD (KR) 2025-03-12 EP disclosed
EP-2968210-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING PEDIATRIC EPILESY BIO PHARM SOLUTIONS CO LTD (KR) 2024-09-11 EP disclosed
US-11931332-B2 Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease BIO-PHARM SOLUTIONS CO., LTD. (KR) 2024-03-19 US disclosed
EP-4204395-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISEASE Bio-Pharm Solutions Co., Ltd. (KR) 2023-07-05 EP disclosed
CN-109939092-B Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndrome 比皮艾思药物研发有限公司 2022-03-22 CN disclosed
US-10525030-B2 Phenyl carbamate compound and a composition for neuroprotection comprising the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2020-01-07 US disclosed
CN-105164103-B Phenyl carbamate compounds and composition for preventing or treating memory loss-related diseases containing the same 比皮艾思药物研发有限公司 2019-12-06 CN disclosed
EP-2613783-B1 METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM IPCA LABORATORIES LTD (IN) 2019-06-12 EP disclosed
US-10105353-B2 Anti-thrombotic compounds IPCA LABORATORIES LIMITED (IN) 2018-10-23 US disclosed
US-9956197-B2 Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndromes BIO-PHARM SOLUTIONS CO., LTD. (KR) 2018-05-01 US disclosed
US-20130165410-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-06-27 US disclosed
US-20130165408-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILESY BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-06-27 US disclosed
US-20130005801-A1 PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-01-03 US disclosed
WO-2013001544-A1 ANTI-THROMBOTIC COMPOUNDS IPCA LABORATORIES LIMITED (IN) 2013-01-03 WO disclosed
EP-2540729-A1 (7aS, 2'S)-2-Oxoclopidogrel as anti-thrombotic compound IPCA Laboratories Limited (IN) 2013-01-02 EP disclosed
US-20120329762-A1 ANTI-THROMBOTIC COMPOUNDS IPCA LABORATORIES LIMITED (IN) 2012-12-27 US disclosed
US-20120329763-A1 ANTI-THROMBOTIC COMPOUNDS IPCA LABORATORIES LIMITED (IN) 2012-12-27 US disclosed
US-20120184762-A1 PROCESS FOR PREPARATION OF PHENYL CARBAMATE DERIVATIVES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2012-07-19 US disclosed
US-20120053157-A1 METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM IPCA LABORATORIES LIMITED (IN) 2012-03-01 US disclosed
WO-2012025942-A1 METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM IPCA LABORATORIES LIMITED (IN) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120329763-A1 ANTI-THROMBOTIC COMPOUNDS TBXA2R, SERPINC1, F2 HTR2A 652/4885HTR2C 273/4885ADRA1A 451/4885
US-20130165408-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILESY CHAT, BCHE, GABBR1 HTR2A 2103/4885HTR2C 2115/4885ADRA1A 3765/4885
US-10105353-B2 Anti-thrombotic compounds TBXA2R, SERPINC1, F2 HTR2A 652/4885HTR2C 273/4885ADRA1A 451/4885
US-20120053157-A1 METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM F2, PLAT, SELP HTR2A 1845/4885HTR2C 1936/4885ADRA1A 1448/4885
US-20130005801-A1 PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME CPT1B, MYLK, PYGM HTR2A 2334/4885HTR2C 1798/4885ADRA1A 513/4885
US-10525030-B2 Phenyl carbamate compound and a composition for neuroprotection comprising the same CHAT, BAX, CASP3 HTR2A 1347/4885HTR2C 2755/4885ADRA1A 3440/4885
US-11931332-B2 Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease SNCA, MAPT, CHAT HTR2A 3487/4885HTR2C 4283/4885ADRA1A 1348/4885
US-20130165410-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE CPS1, PROC, DPP7 HTR2A 3371/4885HTR2C 3341/4885ADRA1A 4254/4885
US-20120184762-A1 PROCESS FOR PREPARATION OF PHENYL CARBAMATE DERIVATIVES CPS1, BCHE, ACHE HTR2A 1462/4885HTR2C 1378/4885ADRA1A 3782/4885
US-20120329762-A1 ANTI-THROMBOTIC COMPOUNDS TBXA2R, SERPINC1, F2 HTR2A 652/4885HTR2C 273/4885ADRA1A 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.