Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22941557 | 0.94 | EGFR (0.39) | SMYD3GRM5KDM4EGAAKMT2A | |
| SCHEMBL22942012 | 0.88 | RAB9A (0.43) | GRM5GAAKMT2ACRBNNPC1 | |
| SCHEMBL22941554 | 0.86 | KCNA3 (0.38) | SMYD3KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22941524 | 0.84 | KDM1A (0.32) | — | |
| SCHEMBL22942059 | 0.83 | RAB9A (0.35) | KDM4EGAAKMT2ANPC1RAB9A | |
| SCHEMBL22941523 | 0.82 | GABRA1 (0.35) | NPC1RAB9A | |
| SCHEMBL22941527 | 0.82 | TAS1R3 (0.41) | SMYD3KDR | |
| SCHEMBL22941978 | 0.82 | JAK2 (0.34) | — | |
| SCHEMBL21344636 | 0.82 | L3MBTL1 (0.44) | GAASMN1; SMN2 | |
| SCHEMBL22942013 | 0.82 | ALOX15 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018834-A1 | CYCLIC DIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |