SCHEMBL22945868

SCHEMBL22945868

COC(=O)Cc1ccccc1/C=C/C1CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
PTGER4 P35408 2/20 0.37
PTGER3 P43115 2/20 0.37
PTGER2 P43116 2/20 0.37
NFE2L2 Q16236 1/20 0.37
GAA P10253 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 2/20 0.35
RORC P51449 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.34
ACHE P22303 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21431146 0.84 MAOA (0.34) KDM4EPTGER4PTGER3PTGER2NFE2L2
SCHEMBL26075997 0.80 KDM4E (0.43) KDM4EPTGER4PTGER3PTGER2NFE2L2
SCHEMBL5026445 0.79 KDM4E (0.42) KDM4EPTGER4PTGER3PTGER2NFE2L2
SCHEMBL9775463 0.78 TRPA1 (0.47) KDM4EPTGER4PTGER3PTGER2NFE2L2
SCHEMBL9775462 0.78 TRPA1 (0.47) KDM4EPTGER4PTGER3PTGER2NFE2L2
SCHEMBL4893812 0.77 ALDH1A1 (0.44) KDM4ENFE2L2ALDH1A1MAPTMEN1
SCHEMBL6970363 0.76 MAPT (0.35) KDM4ENFE2L2GAAALDH1A1MAPT
SCHEMBL8137962 0.76 MAPT (0.35) KDM4ENFE2L2GAAALDH1A1MAPT
SCHEMBL8137959 0.76 MAPT (0.35) KDM4ENFE2L2GAAALDH1A1MAPT
SCHEMBL9011882 0.75 ALDH1A1 (0.43) KDM4ENFE2L2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210032190-A1 CYCLOPROPYL ETHYLENE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032190-A1 CYCLOPROPYL ETHYLENE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME CYC1, EEF1A1, RPS4X KDM4E 280/4885PTGER4 13/4885PTGER3 193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.