Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21127875 | 0.81 | LTA4H (0.35) | KMT2ARAB9AKDM4EALDH1A1KDM1A | |
| SCHEMBL21127876 | 0.81 | POLB (0.51) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL807388 | 0.79 | LMNA (0.50) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL14625789 | 0.79 | ALDH1A1 (0.54) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL5363107 | 0.78 | CXCR4 (0.48) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL15084308 | 0.77 | LMNA (0.51) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL13375730 | 0.76 | KDM4E (0.44) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL13374347 | 0.75 | KDM4E (0.43) | KMT2ARAB9APOLBGAALMNA | |
| SCHEMBL5363103 | 0.75 | LMNA (0.52) | KMT2ARAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL12203995 | 0.74 | KDM4E (0.51) | KMT2ARAB9APOLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339943-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVES | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230339943-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVES | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-11725009-B2 | Anti-influenza virus pyrimidine derivative | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-08-15 | — | — | US | disclosed |
| US-11725009-B2 | Anti-influenza virus pyrimidine derivative | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-08-15 | — | — | US | disclosed |
| US-20220135558-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-05-05 | — | — | US | disclosed |
| US-11136319-B2 | Anti-influenza virus pyrimidine derivative | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2021-10-05 | — | — | US | disclosed |
| US-20210032238-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725009-B2 | Anti-influenza virus pyrimidine derivative | ENTPD5, NUDT15, ITPA | KMT2A 2360/4885RAB9A 862/4885POLB 390/4885 |
| US-20220135558-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | ENTPD5, NUDT15, ITPA | KMT2A 2360/4885RAB9A 862/4885POLB 390/4885 |
| US-20230339943-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVES | ENTPD5, NUDT1, ITPA | KMT2A 2307/4885RAB9A 907/4885POLB 296/4885 |
| US-20210032238-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | ENTPD5, NUDT15, ITPA | KMT2A 2360/4885RAB9A 862/4885POLB 390/4885 |
| US-11136319-B2 | Anti-influenza virus pyrimidine derivative | ENTPD5, NUDT15, ITPA | KMT2A 2360/4885RAB9A 862/4885POLB 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.