SCHEMBL2294732

SCHEMBL2294732

O=C(O)c1ccccc1-c1ccc(O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.66
HNF4A P41235 1/20 0.60
BCAT2 O15382 1/20 0.53
LTB4R2 Q9NPC1 3/20 0.52
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 1/20 0.52
POLB P06746 1/20 0.51
KMT2A Q03164 3/20 0.50
GAA P10253 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
FABP3 P05413 1/20 0.50
FABP4 P15090 1/20 0.50
FABP5 Q01469 1/20 0.50
ABL1 P00519 1/20 0.50
ABCB1 P08183 1/20 0.50
BCR P11274 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902600 0.98 HSD17B10 (0.63) HSD17B10HNF4ABCAT2LTB4R2ALDH1A1
SCHEMBL30292805 0.91 HNF4A (0.63) HSD17B10HNF4ABCAT2LTB4R2ALDH1A1
SCHEMBL18759613 0.91 HNF4A (0.63) HSD17B10HNF4ABCAT2LTB4R2ALDH1A1
SCHEMBL1252583 0.89 IDE (0.66) HSD17B10HNF4ABCAT2LTB4R2ALDH1A1
SCHEMBL11554621 0.89 HNF4A (0.61) HNF4ABCAT2LTB4R2ALDH1A1ALOX15
SCHEMBL32677769 0.87 HNF4A (0.64) HNF4ABCAT2LTB4R2ALDH1A1ALOX15
SCHEMBL32677772 0.87 HNF4A (0.64) HNF4ABCAT2LTB4R2ALDH1A1ALOX15
SCHEMBL505412 0.87 HNF4A (0.64) HNF4ABCAT2LTB4R2ALDH1A1ALOX15
Benzene SCHEMBL1403559 0.87 HNF4A (0.69) HSD17B10HNF4ABCAT2LTB4R2ALDH1A1
SCHEMBL133057 0.87 HNF4A (0.69) HSD17B10HNF4ABCAT2LTB4R2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220280494-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2022-09-08 US claimed
EP-4021406-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2022-07-06 EP claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
WO-2021041730-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2021-03-04 WO claimed
US-20210000740-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2021-01-07 US claimed
EP-3758701-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2021-01-06 EP claimed
CN-112004538-A Compositions of small molecule therapeutic compounds 德尔宝股份有限公司 2020-11-27 CN claimed
EP-3515407-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2019-07-31 EP claimed
EP-3515408-A1 STABLE COMPOSITIONS FOR INCRETIN MIMETIC COMPOUNDS Delpor, Inc. (US) 2019-07-31 EP claimed
US-20190224122-A1 STABLE COMPOSITIONS FOR INCRETIN MIMETIC COMPOUNDS NATIONAL INSTITUTES OF HEALTH 2019-07-25 US claimed
US-20190224322-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2019-07-25 US claimed
WO-2018057968-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2018-03-29 WO claimed
WO-2018057977-A1 STABLE COMPOSITIONS FOR INCRETIN MIMETIC COMPOUNDS DELPOR, INC. (US) 2018-03-29 WO claimed
US-20090030218-A1 Method For Producing Aminoalcohol Derivative Having Biphenyl Group KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-01-29 US claimed
EP-1932826-A1 METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP Kissei Pharmaceutical Co., Ltd. (JP) 2008-06-18 EP claimed
US-6572843-B1 Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide NOVOZYMES, A/S (DK) 2003-06-03 US claimed
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP claimed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US claimed
JP-1079135-A None JP disclosed
US-4080471-A ANTIARRYTHMIA AKTIEBOLAGET HASSLE (SW) 1978-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030218-A1 Method For Producing Aminoalcohol Derivative Having Biphenyl Group ALDH7A1, DDC, ADH5 HSD17B10 107/4885HNF4A 143/4885BCAT2 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.