Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519060 | 0.83 | HTR6 (0.54) | HTR6NAMPTPTGDR2ABCC9ABCC8 | |
| SCHEMBL13728197 | 0.83 | NAMPT (0.49) | HTR6CNR2NAMPTPTGDR2ABCC9 | |
| SCHEMBL27955163 | 0.83 | ABCC9 (0.54) | HTR6CNR2NAMPTPTGDR2ABCC9 | |
| SCHEMBL13728179 | 0.83 | NAMPT (0.48) | HTR6CNR2NAMPTPTGDR2ABCC9 | |
| SCHEMBL6972429 | 0.79 | ALPL (0.47) | HTR6CNR2ALPLSLC40A1SLC22A12 | |
| SCHEMBL3528957 | 0.79 | ELANE (0.60) | HTR6CNR2ALPLSLC40A1SLC22A12 | |
| SCHEMBL24950118 | 0.79 | HTR6 (0.40) | HTR6CNR2PTGDR2ALPLSLC40A1 | |
| SCHEMBL645001 | 0.78 | ALPL (0.46) | HTR6NAMPTALPLSLC40A1SLC22A12 | |
| SCHEMBL2646108 | 0.78 | ALPL (0.46) | HTR6CNR2ALPLSLC40A1SLC22A12 | |
| SCHEMBL6039108 | 0.78 | SLC22A12 (0.48) | HTR6CNR2ALPLSLC40A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | AFF2, AFF4, AFF1 | HTR6 2660/4885CNR2 3246/4885NAMPT 2050/4885 |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | HTR6 2660/4885CNR2 3246/4885NAMPT 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.