Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 6/20 | 0.48 |
| ▸ | S100A10 | P60903 | 6/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234747 | 0.86 | L3MBTL1 (0.39) | ANXA2S100A10MGLLALDH1A1L3MBTL1 | |
| SCHEMBL2234313 | 0.73 | ANXA2 (0.45) | ANXA2S100A10MGLLALDH1A1LMNA | |
| SCHEMBL2295548 | 0.69 | ANXA2 (0.55) | ANXA2S100A10PLK1ALDH1A1L3MBTL1 | |
| SCHEMBL27449104 | 0.64 | ALDH1A1 (0.64) | PLK1THRBALDH1A1L3MBTL1TDP1 | |
| SCHEMBL14098923 | 0.61 | KMT2A (0.61) | PLK1THRBALDH1A1L3MBTL1LMNA | |
| SCHEMBL19875785 | 0.60 | PLK1 (0.47) | PLK1THRBALDH1A1L3MBTL1TDP1 | |
| SCHEMBL19875784 | 0.60 | PLK1 (0.47) | PLK1THRBALDH1A1L3MBTL1TDP1 | |
| Hydrogen Peroxide SCHEMBL27723527 | 0.60 | CYP1A2 (0.54) | PLK1THRBALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5493944 | 0.59 | CYP1A2 (0.59) | MGLLPLK1TDP1KCNH2CNR2 | |
| SCHEMBL326914 | 0.59 | CYP1A2 (0.59) | MGLLPLK1TDP1KCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |