Glyphosate

Glyphosate

SCHEMBL2296082

CCCN.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ANPEP P15144 3/20 0.35
▸ HDAC3 O15379 2/20 0.34
▸ HDAC1 Q13547 2/20 0.34
▸ HDAC2 Q92769 2/20 0.34
▸ HDAC8 Q9BY41 2/20 0.34
▸ FFAR3 O14843 1/20 0.34
▸ GABBR2 O75899 2/20 0.34
▸ GABRR1 P24046 2/20 0.34
▸ GABBR1 Q9UBS5 2/20 0.34
▸ LMNA P02545 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ BLM P54132 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ FDPS P14324 1/20 0.32
▸ GABRR3 A8MPY1 1/20 0.32
▸ GABRP O00591 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyphosate SCHEMBL11567788 1.00 ANPEP (0.35) ANPEPHDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL11565158 0.92 MEN1 (0.36) ANPEPHDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL14742954 0.92 MEN1 (0.36) ANPEPHDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL2293481 0.92 MEN1 (0.36) ANPEPHDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL6056272 0.91 GABBR2 (0.43) ANPEPHDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL2293917 0.90 LMNA (0.37) ANPEPHDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL6056286 0.90 GABBR2 (0.42) GABBR2GABRR1GABBR1TSHRKMT2A
Glyphosate SCHEMBL6056244 0.88 TSHR (0.42) LMNATSHRKMT2AMEN1TDP1
Glyphosate SCHEMBL6056275 0.88 TSHR (0.42) LMNATSHRKMT2AMEN1TDP1
Dodecylamine SCHEMBL7190070 0.88 TSHR (0.42) LMNATSHRKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989392-B2 Herbicidal compositions containing glyphosate bipyridilium MONSANTO TECHNOLOGY, LLC (US) 2011-08-02 — — US claimed
EP-1343375-B1 AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS MONSANTO TECHNOLOGY LLC (US) 2006-08-02 — — EP claimed
US-20060148648-A1 Herbicidal compositions containing glyphosate bipyridilium MONSANTO TECHNOLOGY LLC 2006-07-06 — — US claimed
US-7049270-B2 Potassium glyphosate formulations MONSANTO TECHNOLOGY LLC (US) 2006-05-23 — — US claimed
EP-1343375-A2 AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS Monsanto Technology LLC (US) 2003-09-17 — — EP claimed
US-20030104943-A1 Novel surfactants and formulations MONSANTO TECHNOLOGY LLC 2003-06-05 — — US claimed
WO-2002021924-A2 HERBICIDAL COMPOSITIONS CONTAINING GLYPHOSATE AND BIPYRIDILIUM MONSANTO TECHNOLOGY LLC (US) 2002-03-21 — — WO claimed
WO-2001089302-A2 AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS MONSANTO TECHNOLOGY, LLC (US) 2001-11-29 — — WO claimed
EP-1804578-A2 HIGH-LOAD GLYPHOSATE FORMULATIONS HUNTSMAN PETROCHEMICAL CORPORATION (US) 2007-07-11 — — EP disclosed
US-20060265780-A1 Interaction of glyphosate with photosystem II inhibitor herbicides as a selection tool for roundup ready events MONSANTO TECHNOLOGY LLC (US) 2006-11-23 — — US disclosed
US-20060194699-A1 Sprayable non-aqueous, oil-continuous microemulsions and methods of making same BATTELLE MEMORIAL INSTITUTE 2006-08-31 — — US disclosed
WO-2006041702-A2 HIGH-LOAD GLYPHOSATE FORMULATIONS HUNTSMAN PETROCHEMICAL CORPORATION (US) 2006-04-20 — — WO disclosed
EP-1592299-A1 SPRAYABLE NON-AQUEOUS, OIL-CONTINUOUS MICROEMULSIONS AND METHODS OF MAKING SAME BATTELLE MEMORIAL INSTITUTE (US) 2005-11-09 — — EP disclosed
WO-2004062367-A1 SPRAYABLE NON-AQUEOUS, OIL-CONTINUOUS MICROEMULSIONS AND METHODS OF MAKING SAME BATTELLE MEMORIAL INSTITUTE (US) 2004-07-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060148648-A1 Herbicidal compositions containing glyphosate bipyridilium SYMPK, PTMS, GLO1 ANPEP 96/4885HDAC3 3226/4885HDAC1 4179/4885
US-20030104943-A1 Novel surfactants and formulations PHOSPHO1, GNMT, DDT ANPEP 586/4885HDAC3 4088/4885HDAC1 3867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback