Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 11/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599451 | 0.82 | ELANE (0.41) | CES1KCNN4KIF11MAPTKMT2A | |
| SCHEMBL4602166 | 0.76 | THRB (0.40) | KCNN4KIF11ALDH1A1CYP1A2 | |
| SCHEMBL27415070 | 0.72 | KIF11 (0.45) | CES1KCNN4KIF11MAPTKMT2A | |
| SCHEMBL580603 | 0.71 | KIF11 (0.43) | KCNN4KIF11ALDH1A1ALOX15 | |
| SCHEMBL17253343 | 0.69 | KIF11 (0.54) | KIF11ALDH1A1 | |
| SCHEMBL6812910 | 0.69 | KIF11 (0.43) | KIF11MAPTKMT2ACYP1A2 | |
| SCHEMBL1096837 | 0.68 | KCNN4 (0.47) | CES1KCNN4KIF11MAPTKMT2A | |
| SCHEMBL5666953 | 0.68 | KCNN4 (0.47) | CES1KCNN4MAPTKMT2AALDH1A1 | |
| SCHEMBL11379208 | 0.68 | CYP2C19 (0.52) | CES1KCNN4MAPTKMT2AALDH1A1 | |
| SCHEMBL5355354 | 0.68 | ALDH1A1 (0.45) | CES1MAPTALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11905236-B2 | Dynamic combinatorial library based on pseudopeptides and its use for the detection of cysteine and other biothiols | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2024-02-20 | — | — | US | disclosed |
| CN-116940585-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-3779449-B1 | DYNAMIC COMBINATORIAL LIBRARY BASED ON PSEUDOPEPTIDES AND ITS USE FOR THE DETECTION OF CYSTEINE AND OTHER BIOTHIOLS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2022-02-23 | — | — | EP | disclosed |
| US-20210139419-A1 | DYNAMIC COMBINATORIAL LIBRARY BASED ON PSEUDOPEPTIDES AND ITS USE FOR THE DETECTION OF CYSTEINE AND OTHER BIOTHIOLS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2021-05-13 | — | — | US | disclosed |
| EP-3779449-A2 | DYNAMIC COMBINATORIAL LIBRARY BASED ON PSEUDOPEPTIDES AND ITS USE FOR THE DETECTION OF CYSTEINE AND OTHER BIOTHIOLS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2021-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139419-A1 | DYNAMIC COMBINATORIAL LIBRARY BASED ON PSEUDOPEPTIDES AND ITS USE FOR THE DETECTION OF CYSTEINE AND OTHER BIOTHIOLS | PTMS, LNPEP, CTH | CES1 3458/4885KCNN4 3542/4885KIF11 4073/4885 |
| US-11905236-B2 | Dynamic combinatorial library based on pseudopeptides and its use for the detection of cysteine and other biothiols | PTMS, LNPEP, CTH | CES1 3458/4885KCNN4 3542/4885KIF11 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.