Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | F12 | P00748 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126851 | 0.75 | CYP1A2 (0.49) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL3299661 | 0.75 | ADORA1 (0.70) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL25324519 | 0.74 | RAB9A (0.51) | ADORA1ADORA3KMT2AMEN1NPC1 | |
| SCHEMBL9504179 | 0.74 | ADORA1 (0.65) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL536849 | 0.70 | BRD4 (0.49) | ADORA3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL822059 | 0.69 | ADORA1 (0.58) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL11172212 | 0.68 | ADORA1 (0.56) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL10999313 | 0.68 | CYP1A2 (0.53) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL9564262 | 0.67 | ADORA1 (0.60) | ADORA1L3MBTL1ADORA3KMT2AMEN1 | |
| SCHEMBL2623093 | 0.67 | L3MBTL1 (0.64) | ADORA1L3MBTL1ADORA3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217805-B2 | Bicyclonucleoside analogues | SANKYO COMPANY, LIMITED (JP) | 2007-05-15 | — | — | US | claimed |
| EP-1201678-B1 | NOVEL BICYCLONUCLEOSIDE ANALOGUES | SANKYO CO (JP) | 2004-09-22 | — | — | EP | claimed |
| US-20040143114-A1 | Novel bicyclonucleoside analogues | SANKYO COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | claimed |
| EP-1201678-A1 | NOVEL BICYCLONUCLEOSIDE ANALOGUES | Sankyo Company, Limited (JP) | 2002-05-02 | — | — | EP | claimed |
| US-7994145-B2 | Bicyclonucleoside analogues | TAKESHI IMANISHI (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20070270370-A1 | Novel bicyclonucleoside analogues | SANKYO COMPANY, LIMITED (JP) | 2007-11-22 | — | — | US | disclosed |
| US-7217805-B2 | Bicyclonucleoside analogues | SANKYO COMPANY, LIMITED (JP) | 2007-05-15 | — | — | US | disclosed |
| EP-1201678-B1 | NOVEL BICYCLONUCLEOSIDE ANALOGUES | SANKYO CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040143114-A1 | Novel bicyclonucleoside analogues | SANKYO COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1201678-A1 | NOVEL BICYCLONUCLEOSIDE ANALOGUES | Sankyo Company, Limited (JP) | 2002-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270370-A1 | Novel bicyclonucleoside analogues | PURB, RNGTT, NSUN2 | ADORA1 177/4885L3MBTL1 705/4885ADORA3 294/4885 |
| US-20040143114-A1 | Novel bicyclonucleoside analogues | PURB, DUT, NSUN2 | ADORA1 158/4885L3MBTL1 409/4885ADORA3 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.