Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079077 | 0.89 | MAPT (0.62) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL9717097 | 0.85 | L3MBTL1 (0.67) | MAPTALDH1A1KMT2AGAALMNA | |
| SCHEMBL7336785 | 0.84 | ALDH1A1 (0.79) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL14880158 | 0.81 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| Tetracaine SCHEMBL9146860 | 0.79 | LMNA (0.72) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| Tetracaine SCHEMBL9146334 | 0.79 | LMNA (0.72) | RAB9AMAPTALDH1A1KMT2ACYP3A4 | |
| SCHEMBL19380056 | 0.78 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL3637857 | 0.76 | NPSR1 (0.75) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL8252721 | 0.76 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21391312 | 0.76 | ROCK2 (0.71) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324899-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | METRO INTERNATIONAL BIOTECH, LLC | 2022-10-13 | — | — | US | disclosed |
| EP-4013766-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | Metro International Biotech, LLC (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030551-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | METRO INTERNATIONAL BIOTECH, LLC (US) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324899-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | NQO1, NAMPT, NADK | RAB9A 1443/4885NPC1 309/4885SMN1; SMN2 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.