SCHEMBL23009529

SCHEMBL23009529

O=C(CC(=O)C1(F)CCCCC1)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PLOD2 O00469 2/20 0.32
PLOD3 O60568 1/20 0.31
PLOD1 Q02809 1/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23009421 0.83 CYP2C19 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL23009491 0.81 ALDH1A1 (0.32) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL23009397 0.78 DGAT1 (0.38) PLOD2PLOD3PLOD1
SCHEMBL23009401 0.78 ADORA3 (0.30)
SCHEMBL23009528 0.73
SCHEMBL23009409 0.72 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL31648396 0.71 PLOD2 (0.37) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL23009404 0.71 MME (0.31)
SCHEMBL23009408 0.69 HSD11B1 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL23009403 0.68 MME (0.33) SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
EP-3778614-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM ALDH1A1 31/4885POLB 1508/4885SMN1; SMN2 3974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.