Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390103 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL232389 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL231245 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL231117 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL7670406 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL233216 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL10889066 | 1.00 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL232859 | 0.98 | KEAP1 (0.58) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL231271 | 0.91 | KEAP1 (0.60) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL9738476 | 0.88 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461375-B2 | Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling | EVONIK RÖHM GMBH (DE) | 2013-06-11 | — | — | US | disclosed |
| EP-2287147-B1 | 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-15 | — | — | EP | disclosed |
| EP-1583733-B1 | IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING | EVONIK ROEHM GMBH (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-8350060-B2 | 2-amino-bicyclo[3.1.0] hexane-2, 6-dicarboxylic ester derivative | Taisho Pharamceutical Co., Ltd. (JP) | 2013-01-08 | — | — | US | disclosed |
| EP-1399409-B1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF SE (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-8258133-B2 | 2-amino-bicyclo[3.1.0]hexane-2, 6-dicarboxylic ester derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-04 | — | — | US | disclosed |
| CN-1596248-B | Phenoxyamine compounds and compositions for delivery of active agents | EMISPHERE TECH INC | 2012-05-09 | — | — | CN | disclosed |
| US-20120028982-A1 | 2-AMINO-BICYCLO[3.1.0]HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120004232-A1 | 2-AMINO-BICYCLO(3.1.0) HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
| US-8076502-B2 | 2-amino-bicyclo(3.1.0) hexane-2,6-dicarboxylic ester derivative | TAISHO PHARMACEUTICALS CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20040171868-A1 | Method for producing (meth) acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | US | disclosed |
| CN-1525953-A | Method for producing (meth) acrylic acid esters | �����ɷ� | 2004-09-01 | — | — | CN | disclosed |
| US-20040158096-A1 | Method for producing (meth)acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | US | disclosed |
| WO-2004063140-A1 | IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING | Röhm GmbH & Co. KG (DE) | 2004-07-29 | — | — | WO | disclosed |
| CN-1514821-A | Method for producing acrylic acid esters | 巴斯福股份公司 | 2004-07-21 | — | — | CN | disclosed |
| EP-1399409-A1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-1399408-A1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-24 | — | — | EP | disclosed |
| US-6500983-B2 | FOR THERAPY OF DISEASES OR CONDITIONS MEDIATED BY OVER-PRODUCTION OF OR OVER-RESPONSIVENESS TO TUMOR NECROSIS FACTOR (TNF) | NOVARTIS AG (CH) | 2002-12-31 | — | — | US | disclosed |
| WO-2002100815-A1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002100814-A1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171868-A1 | Method for producing (meth) acrylic acid esters | ADH1A, ADH5, ADH1C | KEAP1 3038/4885SMN1; SMN2 4194/4885HPGD 972/4885 |
| US-20120028982-A1 | 2-AMINO-BICYCLO[3.1.0]HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE | GRIK4, GRIN2D, GRIN2C | KEAP1 3041/4885SMN1; SMN2 3594/4885HPGD 1861/4885 |
| US-20040158096-A1 | Method for producing (meth)acrylic acid esters | ADH1A, ADH5, ADH1C | KEAP1 3688/4885SMN1; SMN2 2298/4885HPGD 700/4885 |
| US-20120004232-A1 | 2-AMINO-BICYCLO(3.1.0) HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE | GRIK4, GRIN2D, GRIN2C | KEAP1 3136/4885SMN1; SMN2 3603/4885HPGD 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.