Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | RORC | P51449 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282907 | 0.84 | RORC (0.56) | RORCALDH1A1NAMPTKMT2A | |
| SCHEMBL23021430 | 0.81 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL17117257 | 0.80 | ALDH1A1 (0.53) | ALDH1A1POLBNAMPTKMT2ANPSR1 | |
| SCHEMBL12686296 | 0.80 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL21783621 | 0.80 | RORC (0.49) | RORCALDH1A1NAMPTKMT2A | |
| SCHEMBL20282922 | 0.80 | RORC (0.49) | RORCALDH1A1NAMPTKMT2A | |
| SCHEMBL21783706 | 0.77 | RORC (0.47) | RORCALDH1A1NAMPT | |
| SCHEMBL20282923 | 0.77 | RORC (0.47) | RORCALDH1A1NAMPT | |
| SCHEMBL21783730 | 0.76 | RORC (0.41) | PDE4BRORCNAMPTKMT2A | |
| SCHEMBL17117227 | 0.76 | ALDH1A1 (0.56) | PDE4BALDH1A1POLBNAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555065-B1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INT (DE) | 2021-02-24 | — | — | EP | disclosed |