Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | STAT1 | P42224 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12686296 | 0.83 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL23021469 | 0.81 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL23021588 | 0.78 | RORC (0.52) | ALDH1A1NPSR1MEN1KMT2AHRH3 | |
| SCHEMBL28363668 | 0.78 | CHRM4 (0.61) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL14112120 | 0.78 | HRH3 (0.59) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL13873675 | 0.77 | CYP2C9 (0.60) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL20149132 | 0.76 | RORC (0.72) | PDE4BNPSR1MEN1KMT2ACYP2C9 | |
| SCHEMBL14112140 | 0.76 | ALDH1A1 (0.58) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL14112119 | 0.76 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 | |
| SCHEMBL4071469 | 0.76 | TUBB4A (0.53) | RAB9ANPC1SMN1; SMN2MAPTSTAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555065-B1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INT (DE) | 2021-02-24 | — | — | EP | disclosed |