Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23021430 | 0.83 | RAB9A (0.61) | RAB9ASMN1; SMN2NPC1MAPTSTAT1 | |
| SCHEMBL12685865 | 0.81 | MEN1 (0.79) | SMN1; SMN2ALDH1A1POLBNPSR1MEN1 | |
| SCHEMBL23021469 | 0.80 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1MAPTSTAT1 | |
| SCHEMBL28363668 | 0.77 | CHRM4 (0.61) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL14112120 | 0.77 | HRH3 (0.59) | RAB9ASMN1; SMN2NPC1MAPTSTAT1 | |
| SCHEMBL1669460 | 0.76 | KDM4E (0.55) | TP53NPSR1MEN1KMT2AHRH3 | |
| SCHEMBL13873675 | 0.76 | CYP2C9 (0.60) | RAB9ASMN1; SMN2NPC1MAPTSTAT1 | |
| SCHEMBL16178752 | 0.75 | MLNR (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12685798 | 0.75 | FAAH (0.72) | RAB9AMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL19405263 | 0.75 | PDE4B (0.57) | RAB9ASMN1; SMN2NPC1USP30PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | disclosed |