Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | EPOR | P19235 | 5/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060403 | 1.00 | ALDH1A1 (0.42) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL22654029 | 0.83 | CYP2C19 (0.49) | ALDH1A1TDP1L3MBTL1KMT2ALMNA | |
| SCHEMBL12799366 | 0.82 | ALDH1A1 (0.47) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL2059549 | 0.82 | CTRB1 (0.49) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL10315706 | 0.82 | ALDH1A1 (0.47) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL7438541 | 0.82 | CTRB1 (0.49) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL15448254 | 0.82 | ALDH1A1 (0.47) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL842166 | 0.81 | ALDH1A1 (0.50) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| SCHEMBL842164 | 0.81 | ALDH1A1 (0.50) | ALDH1A1EPORHCAR2TDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL28475258 | 0.81 | CTRB1 (0.48) | ALDH1A1EPORHCAR2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | ADH5, HDHD5, ADH1A | ALDH1A1 1003/4885EPOR 3263/4885HCAR2 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.