Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936407 | 0.80 | EGFR (0.39) | MAPTKDM4EEGFR | |
| SCHEMBL29586802 | 0.80 | EGFR (0.39) | MAPTKDM4EEGFR | |
| SCHEMBL7412533 | 0.79 | GABRA1 (0.63) | XDHGABRA1GABRB2MAPTCNR2 | |
| SCHEMBL4873148 | 0.78 | XDH (0.40) | XDHGABRA1GABRB2MAPTCNR2 | |
| SCHEMBL3255732 | 0.77 | GABRA1 (0.46) | XDHGABRA1GABRB2MAPTCNR2 | |
| SCHEMBL7131922 | 0.76 | KMT2A (0.40) | GABRA1GABRB2MAPTMEN1KMT2A | |
| SCHEMBL29790996 | 0.76 | CA2 (0.33) | GABRA1GABRB2KDM4ENPSR1CYP1A2 | |
| SCHEMBL23647876 | 0.76 | CA2 (0.33) | GABRA1GABRB2KDM4ENPSR1CYP1A2 | |
| SCHEMBL3956279 | 0.76 | XDH (0.55) | XDHGABRA1GABRB2MAPTCNR2 | |
| SCHEMBL6283834 | 0.75 | CA12 (0.42) | XDHGABRA1GABRB2MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053979-A1 | MACROCYCLIC TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053979-A1 | MACROCYCLIC TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | TLR7, TLR9, TLR1 | XDH 1929/4885GABRA1 1387/4885GABRB2 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.