Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061099 | 0.89 | XDH (0.48) | XDHALDH1A1KDM4EGABRA1GABRB2 | |
| SCHEMBL18148925 | 0.85 | ALDH1A1 (0.39) | XDHALDH1A1KDM4EPTGDRPTGDR2 | |
| SCHEMBL8479639 | 0.83 | CA12 (0.47) | CA12CA1CA2CA3CA4 | |
| SCHEMBL278481 | 0.80 | KDM4E (0.46) | CA12CA1CA2CA4CA6 | |
| SCHEMBL8479634 | 0.80 | CA12 (0.45) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1953516 | 0.80 | CA12 (0.45) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2053985 | 0.79 | GABRA1 (0.41) | ALDH1A1KDM4EPTGDRPTGDR2GABRA1 | |
| SCHEMBL1908071 | 0.79 | ALDH1A1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2852455 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EPTGDRPTGDR2GABRA1 | |
| SCHEMBL6535892 | 0.77 | GABRA1 (0.39) | ALDH1A1KDM4EPTGDRPTGDR2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813516-B1 | PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS | EASTMAN CHEM CO (US) | 1999-12-01 | — | — | EP | claimed |
| US-6906046-B2 | Pharmaceutical uses and synthesis of benzobicyclooctanes | CELLTECH R & D INC. (US) | 2005-06-14 | — | — | US | disclosed |
| US-20030069305-A1 | Pharmaceutical uses and synthesis of benzobicyclooctanes | CELLTECH R & D, INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2002051851-A2 | PHARMACEUTICAL USES AND SYNTHESIS OF BENZOBICYCLOOCTANES | CELLTECH R & D, INC. (US) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069305-A1 | Pharmaceutical uses and synthesis of benzobicyclooctanes | CXCL8, CASP8, IL18 | CA12 4074/4885CA1 3943/4885CA2 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.