Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23032003 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23031880 | 0.80 | ALDH1A1 (0.35) | ALDH1A1NPC1PARP10F2PRSS1 | |
| SCHEMBL21300883 | 0.75 | LOXL2 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL23031870 | 0.73 | IDO1 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23031885 | 0.73 | — | — | |
| SCHEMBL22815269 | 0.72 | KDM1A (0.48) | ALDH1A1NPC1RAB9APARP10SMN1; SMN2 | |
| SCHEMBL23031872 | 0.70 | LOXL2 (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23031867 | 0.70 | CA2 (0.43) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL22043779 | 0.68 | CYP2D6 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22044273 | 0.68 | GRIN2B (0.44) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |