Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762554 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL28827465 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL29372796 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL25008712 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL28827450 | 0.84 | PKM (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL25009057 | 0.83 | SORT1 (0.41) | ALDH1A1RAB9ANPC1MAPTKDM4E | |
| SCHEMBL6415151 | 0.78 | LMNA (0.56) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL592053 | 0.77 | KDM4E (0.43) | ALDH1A1SMN1; SMN2NPC1MAPTCYP3A4 | |
| SCHEMBL951462 | 0.76 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL29558577 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034904-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID DERIVATIVES OF 3-BROMO-4,5-DIHYDRO-1H-PYRAZOLES | FMC CORPORATION (US) | 2021-02-25 | — | — | WO | disclosed |