Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KYNU | Q16719 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825288 | 0.81 | ATM (0.41) | ATMCTSLCTSSCTRB1CTSK | |
| SCHEMBL2177823 | 0.79 | ATM (0.42) | ATMCTSLCTSSCTRB1CTSK | |
| SCHEMBL254638 | 0.79 | ITGB3 (0.53) | CTSLCTSSCTSKTACR1IDO1 | |
| SCHEMBL24795018 | 0.79 | ITGB3 (0.53) | CTSLCTSSCTSKTACR1IDO1 | |
| SCHEMBL4178755 | 0.79 | ITGB3 (0.53) | CTSLCTSSCTSKTACR1IDO1 | |
| SCHEMBL5162450 | 0.78 | ALDH1A1 (0.47) | CTSLCTSSPOLBCTSK | |
| SCHEMBL31139078 | 0.77 | TRPM8 (0.46) | ATMCTSLCTSSPPARGKYNU | |
| SCHEMBL31139080 | 0.77 | CTSL (0.42) | ATMCTSLCTSSCTSK | |
| SCHEMBL1362502 | 0.77 | ATM (0.77) | ATMCTSLCTSSCTRB1PPARG | |
| SCHEMBL3255533 | 0.77 | ATM (0.77) | ATMCTSLCTSSCTRB1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2023-09-14 | — | — | US | disclosed |
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2023-09-14 | — | — | US | disclosed |
| US-11702431-B2 | Oxo-substituted compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-18 | — | — | US | disclosed |
| US-11702431-B2 | Oxo-substituted compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-18 | — | — | US | disclosed |
| US-11066425-B1 | Oxo-substituted compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| US-20210147448-A1 | OXO-SUBSTITUTED COMPOUND | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-05-20 | — | — | US | disclosed |
| EP-3786168-A1 | OXO-SUBSTITUTED COMPOUND | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702431-B2 | Oxo-substituted compound | CYP51A1, OXA1L, O60361 | ATM 2315/4885CTSL 480/4885CTSS 784/4885 |
| US-11066425-B1 | Oxo-substituted compound | CYP51A1, OXA1L, O60361 | ATM 2315/4885CTSL 480/4885CTSS 784/4885 |
| US-20210147448-A1 | OXO-SUBSTITUTED COMPOUND | CYP51A1, OXA1L, O60361 | ATM 2315/4885CTSL 480/4885CTSS 784/4885 |
| US-20230287009-A1 | OXO-SUBSTITUTED COMPOUND | CYP51A1, OXA1L, O60361 | ATM 2315/4885CTSL 480/4885CTSS 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.