SCHEMBL23040283

SCHEMBL23040283

OC(c1ccccc1[SiH2]C(Cl)Cl)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.37
KCNJ11 Q14654 13/20 0.33
ABCC9 O60706 3/20 0.32
ABCC8 Q09428 3/20 0.32
KCNJ8 Q15842 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23040280 0.74 KCNJ11 (0.34) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2582219 0.73 MEN1 (0.52) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL23040281 0.67 NR1H2 (0.46) SMN1; SMN2NR1H2NR1H3
SCHEMBL24901411 0.66 MEN1 (0.46) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL1873962 0.66 ALDH1A1 (0.50) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL23040269 0.66 NR1H3 (0.37) MEN1KMT2AMAPK1HSD17B10NR1H2
SCHEMBL19746100 0.65 MEN1 (0.44) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3380756 0.65 SMN1; SMN2 (0.55) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL23059981 0.65 ALDH1A1 (0.48) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL5222166 0.65 SMN1; SMN2 (0.46) MEN1KMT2AKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166548-A Resin composition, photosensitive resin composition, cured film, method for producing cured film, patterned cured film, and method for producing patterned cured film 中央硝子株式会社 2021-07-23 CN disclosed
US-20210061827-A1 Silicon Compound Containing Hexafluoroisopropanol Group, and Method for Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2021-03-04 US disclosed
CN-111819183-A Silicon compound containing hexafluoroisopropanol group and method for producing same 中央硝子株式会社 2020-10-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061827-A1 Silicon Compound Containing Hexafluoroisopropanol Group, and Method for Producing Same FOS, FUBP3, SF3A3 MEN1 3408/4885KMT2A 1435/4885KDM4E 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.