SCHEMBL230411

SCHEMBL230411

COc1nc(=O)[nH]cc1C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.34
PDE3B Q13370 3/20 0.33
PDE3A Q14432 3/20 0.33
POLB P06746 1/20 0.33
DYRK1A Q13627 2/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27386731 0.80 ATAD2 (0.32) ATAD2
SCHEMBL8329303 0.79 CDK1 (0.35) ATAD2
SCHEMBL10438124 0.79 MAT2A (0.38) ATAD2POLB
SCHEMBL6231584 0.78 DPYD (0.33)
SCHEMBL4198780 0.75
SCHEMBL766872 0.74 LMNA (0.42) POLB
SCHEMBL4016272 0.73
SCHEMBL8330590 0.71 L3MBTL1 (0.49) POLBDYRK1A
SCHEMBL22008 0.70
SCHEMBL10402389 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4357461-A2 DETERMINATION OF BASE MODIFICATIONS OF NUCLEIC ACIDS The Chinese University Of Hong Kong (CN) 2024-04-24 EP claimed
EP-3827092-B1 DETECTION OF METHYLATION OF NUCLEOTIDES IN NUCLEIC ACIDS UNIV HONG KONG CHINESE (CN) 2024-01-31 EP claimed
EP-3710596-B1 MAPPING THE LOCATION, TYPE AND STRAND OF DAMAGED NUCLEOTIDES IN DOUBLE-STRANDED DNA NEW ENGLAND BIOLABS INC (US) 2023-08-02 EP claimed
CN-112752853-B Determination of base modification of nucleic acids 香港中文大学 2023-06-30 CN claimed
EP-3827092-A1 DETERMINATION OF BASE MODIFICATIONS OF NUCLEIC ACIDS The Chinese University Of Hong Kong (CN) 2021-06-02 EP claimed
CN-112752853-A Determination of base modifications of nucleic acids 香港中文大学 2021-05-04 CN claimed
WO-2021032060-A1 DETERMINATION OF BASE MODIFICATIONS OF NUCLEIC ACIDS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2021-02-25 WO claimed
US-10900071-B2 Identification of genetic modifications WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2021-01-26 US claimed
US-20190040457-A1 IDENTIFICATION OF GENETIC MODIFICATIONS WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2019-02-07 US claimed
US-5866700-A Solid-phase synthesis of oligoribonucleotides HOECHST AKTIENGESELLSCHAFT (DE) 1999-02-02 US claimed
CN-122095107-A Enrichment of clinically relevant nucleic acids 2026-05-26 CN disclosed
US-20260132223-A1 CLEAVABLE LINKERS FOR THE TETHERING OF POLYMERASES TO NUCLEOTIDES ANSA BIOTECHNOLOGIES INC (US) 2026-05-14 US disclosed
US-20260132442-A1 SPATIALLY RESOLVED SURFACE CAPTURE OF NUCLEIC ACIDS ELEMENT BIOSCIENCES INC (US) 2026-05-14 US disclosed
US-20260125751-A1 CYANINE DERIVATIVES AND RELATED USES ELEMENT BIOSCIENCES INC (US) 2026-05-07 US disclosed
EP-4731762-A2 DE NOVO STEPWISE TEMPLATE-INDEPENDENT SYNTHESIS OF LONG POLYNUCLEOTIDES Ansa Biotechnologies, Inc. (US) 2026-04-29 EP disclosed
EP-0630381-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. ACAD OF SCIENCE CZECH REPUBLIC (CS) 1994-12-28 EP disclosed
US-5359067-A Process for the preparation of 5-substituted cytosines and other 4,5-disubstituted pyrimidin-2(1H)-ones, and intermediates arising in the course of this HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-25 US disclosed
EP-0544210-A1 Process for the preparation of in position 5 substituted cytosines and of other 4,5-disubstituted pyrimidin-2(1H)-ones, also the forth-issuing intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-02 EP disclosed
WO-1993007157-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1993-04-15 WO disclosed
EP-0132127-B1 CYCLIC UREA CONDENSATES, TEXTILE AND PAPER TREATING COMPOSITIONS AND NOVEL CYCLIC UREAS SEQUA CHEMICALS INC. (US) 1993-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125751-A1 CYANINE DERIVATIVES AND RELATED USES NSUN2, NSUN3, AS3MT ATAD2 3984/4885PDE3B 3342/4885PDE3A 3974/4885
US-20260132442-A1 SPATIALLY RESOLVED SURFACE CAPTURE OF NUCLEIC ACIDS POLM, RNGTT, CPSF6 ATAD2 3228/4885PDE3B 4871/4885PDE3A 4868/4885
US-20260132223-A1 CLEAVABLE LINKERS FOR THE TETHERING OF POLYMERASES TO NUCLEOTIDES POLN, PCNA, POLB ATAD2 1241/4885PDE3B 4565/4885PDE3A 4213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.